Purpose: In recent years, there has been an increase in the number of elderly patients undergoing surgery for esophageal squamous cell carcinoma (ESCC). However, there are few studies on short- and long-term outcomes of minimally invasive esophagectomy (MIE) in such patients. The purpose of this study was to report both short- and long-term outcomes of MIE in elderly patients with ESCC.
Methods: A total of 273 patients with ESCC underwent MIE at our hospital from January 2010 to December 2016. Patients were divided into elderly (≥70 years) and nonelderly (<70 years) groups based on age at the time of surgery. Groups were compared with regard to general preoperative data, intraoperative data, postoperative 30-day complications and their severity, pathological result, recurrence, overall survival (OS), and disease-free survival (DFS) rates.
Results: The elderly group was characterized by higher Charlson Comorbidity Index >2 and American Society of Anesthesiologists (ASA) grade. Comparisons of other general preoperative data showed no significant differences. In addition, there were no significant differences in short-term outcomes except for postoperative 30-day complication rate. Although 30-day postoperative complication rate was higher in the elderly group compared with the nonelderly group, the incidence of major complications was similar between groups. Cancer recurrence, 5-year OS, and 5-year DFS rates also were similar between groups.
Conclusion: Although elderly patients with ESCC had higher Charlson Comorbidity Index and ASA grade, they could achieve short- and long-term outcomes of MIE similar to those of nonelderly patients.
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Obes Surg
January 2025
Ziekenhuis Groep Twente, Almelo, Netherlands.
Background: This study aimed to create a comprehensive Core Outcome Set (COS) for assessing the long-term outcome (≥ 5 years) after Metabolic Bariatric Surgery (MBS), through the use of the Delphi method.
Methods: The study utilized a three-phase approach. In Phase 1, a long list of items was identified through a literature review and expert input, forming the basis for an online Delphi survey.
J Endovasc Ther
January 2025
Angiology, HFR Fribourg, Hôpital Universitaire et Cantonal, Fribourg, Switzerland.
Purpose: Angioplasty of lower extremity arteries with calcification may result in flow-limiting dissection requiring bail-out stenting with unfavorable long-term outcomes. Vessel preparation prior to angioplasty may improve immediate results of the angioplasty and long-term patency. This prospective study assessed the 12-month outcomes of patients who underwent novel vessel preparation catheter, the FLEX Vessel Prep™ System (FLEX VP), prior to drug-coated balloon angioplasty (DCB-PTA).
View Article and Find Full Text PDFALTEX
January 2025
Laboratory of Hepato-Gastroenterology, Institute of Experimental and Clinical Research, UCLouvain, Brussels, Belgium.
The gut microbiota is unanimously acknowledged as playing a central role in human health, notably through the production of various metabolites, including short-chain fatty acids, secondary bile acids, vitamins or neurotransmitters. Beyond contributing to gut health itself, these microbial metabolites significantly impact multiple organ systems by participating in key signaling pathways along the well documented gut-organ axes. Chemicals ingested through food might interact with our gut microbiota, altering metabolites production with consequences on health.
View Article and Find Full Text PDFZhongguo Dang Dai Er Ke Za Zhi
January 2025
Anemia of prematurity (AOP) is a multifactorial condition associated with congenital iron deficiency, low erythropoietin levels, a short lifespan of red blood cells, and iatrogenic blood loss. AOP is a common complication in premature infants that can adversely affect growth, development, and long-term neurocognitive outcomes. To standardize the diagnosis and treatment of AOP, the Neonatal Clinical Practice Guidelines Expert Committee and the Neonatal Evidence-Based Medicine Group of the Commission of Neonatal Medicine of the Cross-Strait Medical and Health Exchange Association, along with the Editorial Office of the , have developed the "Clinical practice guidelines for the diagnosis and treatment of anemia of prematurity (2025)", based on the World Health Organization's handbook for guideline development and the formulation/revision principles of Chinese clinical practice guidelines.
View Article and Find Full Text PDFHealth Econ
January 2025
Department of Economics, Federal University of Pelotas (UFPEL), Pelotas, Brazil.
The Northeast region of Brazil is characterized by long periods of drought. However, the region is also frequently affected by floods. The socioeconomic characteristics of the locality make the population more vulnerable to the impacts of these disasters.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!