Using Correlative Properties of Neighboring Pixels to Improve Gray-White Differentiation in Pediatric Head CT Images.

AJNR Am J Neuroradiol

Mallinckrodt Institute of Radiology (A.S., C.H., M.P.), Washington University School of Medicine, Washington University, St. Louis, Missouri.

Published: March 2018

Background And Purpose: A lower radiation dose can have a detrimental effect on the quality of head CT images. The aim of this study performed in a pediatric population was to test whether an image-processing algorithm (Correlative Image Enhancement) based on the correlation among intensities of neighboring pixels can improve gray-white differentiation in head CTs.

Materials And Methods: Sixty baseline head CT images with normal findings obtained from scans of 30 children were processed using Correlative Image Enhancement to produce corresponding enhanced images. Gray-white differentiation in baseline and enhanced images was assessed quantitatively by calculating the contrast-to-noise ratio and conspicuity in equivalent ROIs in gray and white matter. Two masked readers rated the images for visibility of gray-white differentiation on a 5-point Likert scale. Differences in both quantitative and qualitative measures of gray-white differentiation between baseline and enhanced images were tested for statistical significance. values < .05 were considered significant.

Results: Image processing resulted in improvement in the contrast-to-noise ratio (from 1.86 ± 0.94 to 2.26 ± 1.00, = .02) as well as conspicuity (from 37.28 ± 11.56 to 46.4 ± 11.5, < .001). This was accompanied by improved subjective visibility of gray-white differentiation as reported by both readers ( < .01).

Conclusions: Image processing using Correlative Image Enhancement had a beneficial effect on quantitative measures of gray-white differentiation. This translated into improved perception of gray-white differentiation by readers. Further studies are needed to assess the effect of such image processing on the detection of disease processes using head CTs.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655315PMC
http://dx.doi.org/10.3174/ajnr.A5506DOI Listing

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