Background And Purpose: A lower radiation dose can have a detrimental effect on the quality of head CT images. The aim of this study performed in a pediatric population was to test whether an image-processing algorithm (Correlative Image Enhancement) based on the correlation among intensities of neighboring pixels can improve gray-white differentiation in head CTs.
Materials And Methods: Sixty baseline head CT images with normal findings obtained from scans of 30 children were processed using Correlative Image Enhancement to produce corresponding enhanced images. Gray-white differentiation in baseline and enhanced images was assessed quantitatively by calculating the contrast-to-noise ratio and conspicuity in equivalent ROIs in gray and white matter. Two masked readers rated the images for visibility of gray-white differentiation on a 5-point Likert scale. Differences in both quantitative and qualitative measures of gray-white differentiation between baseline and enhanced images were tested for statistical significance. values < .05 were considered significant.
Results: Image processing resulted in improvement in the contrast-to-noise ratio (from 1.86 ± 0.94 to 2.26 ± 1.00, = .02) as well as conspicuity (from 37.28 ± 11.56 to 46.4 ± 11.5, < .001). This was accompanied by improved subjective visibility of gray-white differentiation as reported by both readers ( < .01).
Conclusions: Image processing using Correlative Image Enhancement had a beneficial effect on quantitative measures of gray-white differentiation. This translated into improved perception of gray-white differentiation by readers. Further studies are needed to assess the effect of such image processing on the detection of disease processes using head CTs.
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http://dx.doi.org/10.3174/ajnr.A5506 | DOI Listing |
Glia
December 2024
Faculty of Medicine, Experimental Epilepsy Research, Department of Neurosurgery, Medical Center - University of Freiburg, Freiburg, Germany.
Focal cortical dysplasias (FCDs) are local malformations of the human neocortex and a leading cause of intractable epilepsy. FCDs are classified into different subtypes including FCD IIa and IIb, characterized by a blurred gray-white matter boundary or a transmantle sign indicating abnormal white matter myelination. Recently, we have shown that myelination is also compromised in the gray matter of FCD IIa of the temporal lobe.
View Article and Find Full Text PDFClin Nucl Med
December 2024
GE HealthCare, Waukesha, WI.
We report a case of a 33-year-old man with epilepsy and equivocal EEG, MRI signs of mesiotemporal sclerosis, and nondiagnostic standard FDG-PET imaging. The patient underwent repeat FDG-PET/MRI to clarify the sidedness of the epileptogenic focus and to confirm the suspected MTS. The standard PET reconstruction using block sequential regularized expectation maximization failed to provide evidence of a clear epileptogenic focus.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
November 2024
Pirogov Russian National Research Medical University, Moscow, Russia.
Histol Histopathol
October 2024
Department of Pathology, Guang'an Men Hospital, China Academy of Chinese Medical Sciences, Beijing, PR China.
Objective: To explore the clinicopathological and morphological characteristics, diagnosis, differential diagnosis, treatment, and prognosis of primary signet-ring cell/histiocytoid carcinoma (SRCHC) of the axilla.
Methods: The clinical manifestations, pathomorphological characteristics, and immunohistochemical staining results of a case of primary SRCHC in the axilla were retrospectively analyzed, and the relevant literature was reviewed.
Results: The patient was a 69-year-old male.
Diseases
October 2024
Department of Radiology, Tokyo Medical University Hospital, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.
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