Molecular Research on Drug Induced Liver Injury.

Int J Mol Sci

Pharmacovigilance Consultancy, 75020 Paris, France.

Published: January 2018

Drugs may cause liver injury in a few susceptible individuals, but the molecular events that lead to this idiosyncratic, largely dose-independent and non-predictable drug-induced liver injury (DILI) are mostly unknown, since animal models to explore the pathogenetic mechanisms of human idiosyncratic DILI are not yet reliable.[...].

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796165PMC
http://dx.doi.org/10.3390/ijms19010216DOI Listing

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