This medical record review examines the novel use of low-dose trifluoperazine, a high-potency typical antipsychotic, in a cohort of patients with Morgellons disease.
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| http://dx.doi.org/10.1001/jamadermatol.2017.5175 | DOI Listing |
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Patients with Morgellons disease have a lower quality of life than patients with psoriasis, atopic dermatitis and prurigo nodularis.
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Department of Dermatology, Oregon Health and Science University, Portland, OR, USA.
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Department of Psychiatry, Essex Partnership University NHS Foundation Trust, Colchester, GBR.
Article Synopsis
- Delusional infestation (DI) is a psychological condition where individuals wrongly believe they are infested with parasites or other pathogens, despite lacking any medical evidence.
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The purpose of this report is to present a case of a 63-year-old man with orbital Morgellons disease. A 63-year-old man presented reporting 15 years of daily egress of different foreign bodies apparently found in the superior fornices of both eyes, exhibiting a classic manifestation known as the matchbox sign. He described the symptoms starting after a facial trauma.
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Morgellons disease: a narrative review.
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Department of Dermatology, Hospital das Clínicas of the Faculty of Medicine of the University of São Paulo, São Paulo, Brazil.
Morgellons disease is characterized by the persistent delusion of skin infestation, ultimately inflicting wounds and impairing quality of life. There is insufficient and conflicting research pertaining to this condition, imposing challenges on clinicians in understanding, diagnosing, and treating it. In this review, we summarize the available literature on Morgellons disease including its historical evolution, epidemiology, proposed pathophysiology, underlying structural and functional brain pathologies, typical and atypical clinical presentations, diagnosis, and treatment.
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