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| http://dx.doi.org/10.1016/j.eucr.2017.11.001 | DOI Listing |
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A Proposal for Revised and Simplified Renal Pelvic Urothelial Carcinoma Staging Criteria: A Clinicopathologic Study of 141 Tumors.
Am J Surg Pathol
November 2024
Department of Pathology, Massachusetts General Hospital.
Staging of renal pelvic urothelial carcinoma can be challenging due to anatomic variation at the renal pelvis compared with ureter and bladder and calls into question the prognostic accuracy of the current TNM staging. In this study, we determined staging and cancer-specific survival (CSS) in 141 patients undergoing nephroureterectomy for renal pelvic urothelial carcinoma (pTa=50, pT1=29, pT2=10, pT3=36, and pT4=16). Under current staging criteria, we found no significant difference in CSS between adjacent staging categories step-wise across pTa, pT1, pT2, and pT3 tumors.
View Article and Find Full Text PDF[An unusual variant of intrarenal refluxes in the renal sinus cyst].
Urologiia
July 2024
Urologic Clinic of the European Medical Center", Moscow, Russia.
The intrarenal reflux is caused by impaired emptying of the renal pelvis, that leads to increased intrarenal pressure. Increased pelvis pressure can be the result of a variety of states. The most common causes are acute upper urinary tract obstruction or overfilling of the pelvis during retrograde intrarenal surgery (RIRS) or retrograde pyelography.
View Article and Find Full Text PDFVEGFC Overexpression in Kidney Progenitor Cells Is a Model of Renal Lymphangiectasia-Brief Report.
Arterioscler Thromb Vasc Biol
January 2025
Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL.
Background: Lymphangiogenesis is believed to be a protective response in the setting of multiple forms of kidney injury and mitigates the progression of interstitial fibrosis. To augment this protective response, promoting kidney lymphangiogenesis is being investigated as a potential treatment to slow the progression of kidney disease. As injury-related lymphangiogenesis is driven by signaling from the receptor VEGFR3 (vascular endothelial growth factor receptor 3) in response to the cognate growth factor VEGF (vascular endothelial growth factor)-C released by tubular epithelial cells, this signaling pathway is a candidate for future kidney therapeutics.
View Article and Find Full Text PDFFlexible ureteroscopic incision and drainage or laparoscopic unroofing for the parapelvic renal cysts: A systematic review and meta‑analysis.
Exp Ther Med
September 2024
Department of Urology, The First Affiliated Hospital of Huzhou Normal College, Huzhou, Zhejiang 313000, P.R. China.
The aim of the present study was to compare flexible ureteroscopy and laparoscopy in the treatment of peripelvic renal cysts, so as to determine the best treatment method for patients with peripelvic renal cysts. A systematic search of the PubMed, EMBASE, Cochrane Library, CONAHL, Clinicaltrials.gov, Google Scholar, CNKI and WanFang DATA databases was conducted for articles published over 22 years (December 1980-December 2022) using the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines.
View Article and Find Full Text PDFBilateral renal lymphangiectasia: Literature review of a rare entity.
Saudi Med J
May 2024
From the Department of Surgery (Ayed), from the Department of Pathology (Sohail, Rizvi), College of Medicine, University of Bisha; and from the Department of Urology (Alwadai), King Abdullah Hospital, Ministry of Health, Bisha, Kingdom of Saudi Arabia.
Article Synopsis
- Renal lymphangiectasia (RL) is a rare condition characterized by dilated lymphatic vessels leading to cysts in various kidney locations, and its understanding largely stems from individual case reports.
- The condition can be genetic or acquired, affects individuals of any gender or age, and often presents as abdominal or flank pain, being either focal or diffuse and unilateral or bilateral.
- Diagnosis relies on imaging techniques, and while treatment is typically conservative, there is a need for long-term monitoring for complications like hypertension and renal vein thrombosis; a case of bilateral RL is discussed alongside a literature review.
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