Trifluoromethyl vinyl sulfide, a potential building block for pharmaceutically and agrochemically relevant products, is prepared and used for the first time in high-pressure-mediated 1,3-dipolar cycloaddition reactions with nitrones to synthesize (trifluoromethyl)sulfanyl isoxazolidines.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822222PMC
http://dx.doi.org/10.1021/acs.joc.7b02639DOI Listing

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