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Augmented prediction of vertebral collapse after osteoporotic vertebral compression fractures through parameter-efficient fine-tuning of biomedical foundation models.
Sci Rep
December 2024
Department of Medical Device Development, Seoul National University College of Medicine, Seoul, Republic of Korea.
Vertebral collapse (VC) following osteoporotic vertebral compression fracture (OVCF) often requires aggressive treatment, necessitating an accurate prediction for early intervention. This study aimed to develop a predictive model leveraging deep neural networks to predict VC progression after OVCF using magnetic resonance imaging (MRI) and clinical data. Among 245 enrolled patients with acute OVCF, data from 200 patients were used for the development dataset, and data from 45 patients were used for the test dataset.
View Article and Find Full Text PDFEfficacy and Safety of Tranexamic Acid on Hidden Blood Loss in Osteoporotic Vertebral Compression Fractures Patients Treated with Percutaneous Kyphoplasty: A Prospective Randomized Controlled Trial.
Ther Clin Risk Manag
December 2024
Department of Orthopedics, Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, People's Republic of China.
Purpose: To evaluate the efficacy and safety of intravenous tranexamic acid (TXA) in patients undergoing percutaneous kyphoplasty (PKP), and identify the factors influencing hidden blood loss (HBL).
Methods: This randomized, placebo-controlled trial included 146 patients undergoing PKP surgery from September 2023 to July 2024. Patients were randomly assigned into the TXA group (75 patients received 1.
Association between bone mineral density and scoliosis: a two-sample mendelian randomization study in european populations.
Hereditas
December 2024
Department of Pediatric Spine Surgery, Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou, China.
Background: Previous studies have shown that bone mineral density (BMD) has a certain impact on scoliosis. However, up to now, there is no clear evidence that there is a causal association between the two. The aim of this study is to investigate whether there is a causal association between BMD at different body positions and scoliosis by two-sample Mendelian randomization (MR).
View Article and Find Full Text PDFMeta-analysis of minimally invasive transforaminal lumbar interbody fusion versus oblique lumbar interbody fusion for treating lumbar degenerative diseases.
J Orthop Surg Res
December 2024
Department of Spine Surgery, The First Affiliated Hospital of Guangxi Medical University, 6 Shuangyong Road, Nanning, 530021, Guangxi Zhuang Autonomous Region, China.
Objective: This study aims to perform a meta-analysis that integrates multiple literature sources to evaluate the clinical efficacy of oblique lumbar interbody fusion (OLIF) versus minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) for treating lumbar degenerative diseases (LDD).
Methods: A systematic search was conducted across various databases, including CNKI, VIP, WANFANG DATA, SinoMed, PubMed, Cochrane Library, Embase, and Web of Science, for clinical comparative studies on OLIF and MIS-TLIF for treating LDD, covering the time frame from the inception of the databases to September 2024. Following PRISMA guidelines, studies were screened, assessed, and data were extracted rigorously.
Multisite pain among United States Veterans with Posttraumatic Stress Disorder: Prevalence, predictors, and associations with symptom clusters.
J Pain
December 2024
United States Department of Veteran Affairs Center of Excellence for Stress and Mental Health, 3350 La Jolla Village Dr, San Diego, CA, USA; San Diego Veteran Affairs Healthcare System, 3350 La Jolla Village Dr, San Diego, CA, USA; Department of Psychiatry, University of California San Diego, 9500 Gilman Dr, La Jolla, CA, USA. Electronic address:
Persistent pain in multiple distinct body sites is associated with poorer functional outcomes above and beyond pain intensity and interference. Veterans, and especially those with post-traumatic stress disorder (PTSD), may be at risk for multisite pain. However, the research to date characterizing this presentation is limited.
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