Primary Jejunal Adenocarcinoma Presenting as Bilateral Ovarian Metastasis.

Gastroenterology Res

Department of Gastroenterology and Hepatology, The Brooklyn Hospital Center, Academic Affiliate of The Icahn School of Medicine at Mount Sinai, Clinical Affiliate of The Mount Sinai Hospital, 121 Dekalb Avenue, Brooklyn, NY 11201, USA.

Published: December 2017

Small intestinal tumors are rare with adenocarcinoma of the small intestine accounting for less than 2% of all gastrointestinal cancers. Primary jejunal adenocarcinoma constitutes a minute portion of small intestine adenocarcinomas. Clinically, this cancer presents at latter stages of its progression, mainly due to vague and non-specific symptoms, and the difficulty encountered in accessing the jejunum on upper endoscopy. Diagnosis of jejunal adenocarcinoma is usually inconclusive with the use of computed tomography (CT) scan, small bowel series, or upper endoscopy. Laparoscopy followed by frozen section biopsy provides a definitive diagnosis. In the past decade, balloon-assisted enteroscopy (BAE) and capsule endoscopy have become popular as useful modalities for diagnosing small bowel diseases. Wide excisional jejunectomy is the only treatment option with an estimated 5-year survival of 40-65%. Physicians are advised to suspect jejunal adenocarcinoma as a differential diagnosis in patients who present with non-specific symptoms of abdominal pain, nausea, vomiting, weight loss, anemia, gastrointestinal bleeding or signs of small bowel obstruction. We present a rare case of a 37-year-old woman with suspected bilateral ovarian masses, which was immunohistochemically confirmed as primary jejunal adenocarcinoma with bilateral ovarian metastasis.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755639PMC
http://dx.doi.org/10.14740/gr879wDOI Listing

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Article Synopsis
  • * It presents a specific case of an 89-year-old man with SBO due to jejunal adenocarcinoma that invaded hernia mesh from previous surgery, highlighting how his cancer and prior treatments contributed to the obstruction.
  • * The findings suggest a complex relationship between surgical history, cancer progression, and SBO, emphasizing the need for careful management due to the significant healthcare costs associated with these conditions.
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