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Ovarian cancer prevention through opportunistic salpingectomy during abdominal surgeries: A cost-effectiveness modeling study.
PLoS Med
January 2025
Department of Gynecology and Reproductive Medicine, University Hospital Jena, Friedrich Schiller University Jena, Jena, Germany.
Background: There is indication that the fallopian tubes might be involved in ovarian cancer pathogenesis and their removal reduces cancer risk. Hence, bilateral salpingectomy during hysterectomy or sterilization, so called opportunistic salpingectomy (OS), is gaining wide acceptance as a preventive strategy. Recently, it was discussed whether implementation of OS at other gynecologic surgery, e.
View Article and Find Full Text PDFOrigin and In-Office Treatment of Retrograde Cricopharyngeus Dysfunction.
JAMA Otolaryngol Head Neck Surg
January 2025
Department of Otolaryngology-Head and Neck Surgery, Foch Hospital, School of Medicine, Paris Saclay University, Paris, France.
Importance: Retrograde cricopharyngeus dysfunction (R-CPD) is an emerging disorder associated with disabling symptoms. The origin of R-CPD remains unknown.
Objective: To investigate the development of symptoms, diagnosis approach, and therapeutic outcomes of R-CPD in patients treated with in-office botulinum toxin injection (BTI) into the cricopharyngeus.
Primary Leiomyosarcoma of the Thyroid.
Head Neck Pathol
January 2025
Department of medical oncology, Habib Bourguiba Hospital, University of Sfax, Sfax, 3029, Tunisia.
Leiomyosarcoma (LMS) is a malignant mesenchymal neoplasm showing smooth muscle differentiation. Primary LMS of the thyroid gland is quite rare, accounting for only 0.014% of cases.
View Article and Find Full Text PDFCost-Effective Quality of Life Improvement While Reducing Health Care Professional Burnout With an AI-Driven Intervention for Personalized Medicine.
J Diabetes Sci Technol
January 2025
Spotlight Consultations Ltd, Portsmouth, UK.
Background And Aims: Burnout affects >50% of physicians and nurses. Spotlight-AQ is a personalized digital health platform designed to improve routine diabetes visits. We assessed cost-effectiveness, visit length, and association with health care professional (HCP) burnout.
View Article and Find Full Text PDFIs there a risk of esketamine misuse in clinical practice?
Ther Adv Drug Saf
January 2025
Pharmacology Department, School of Medicine, University of Valladolid, Valladolid, Spain.
In 2019, intranasal esketamine gained approval as a promising therapy for those individuals grappling with treatment-resistant depression. Both clinical trials and real-world studies have underscored its efficacy in alleviating and remitting depressive symptoms, with sustained benefits observed for nearly 4.5 years.
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