AI Article Synopsis
- Fusobacterium nucleatum is a harmful, anaerobic bacteria that lives in various human body systems, often linked to infections like periodontal disease.
- There have been no prior reports of this specific bacteria causing acute joint infections around prosthetic implants.
- This case study presents the first documented instance of a severe knee prosthetic infection from F. nucleatum in a healthy patient, which did not respond to a treatment method known as DAIR (Debridement, Antibiotics, and Implant Retention).
Article Abstract
Fusobacterium nucleatum is an obligately anaerobic gram-negative rod, a component of the microbiome of the oropharynx and the gastrointestinal and urogenital tracts, causing an array of human infections which often include periodontal pathologies. As far as we know, there are no previous publications about acute periprosthetic joint infection due to Fusobacterium sp.; we report the first case in the medical literature of an aggressive, acute knee prosthetic infection due to F. nucleatum in a non-immunocompromised patient, unsuccessfully treated with a DAIR approach (Debridement + Antibiotics + Implant Retention).
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| http://dx.doi.org/10.1016/j.anaerobe.2017.12.010 | DOI Listing |
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