Vedolizumab-induced acute pancreatitis: the first reported clinical case.

BMJ Case Rep

Department of Gastroenterology, Royal Perth Hospital, Perth, Western Australia, Australia.

Published: January 2018

Drug-induced acute pancreatitis (DIAP) is a rare, but clinically significant diagnosis. Vedolizumab, an αβ integrin inhibitor, which was approved in 2015 for treatment of moderate to severe inflammatory bowel disease, is a well-tolerated medication with a favourable safety profile and minimal serious adverse events in premarketing clinical trials. We present the first reported case of acute pancreatitis directly attributable to vedolizumab.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775808PMC
http://dx.doi.org/10.1136/bcr-2017-222554DOI Listing

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