A PHP Error was encountered

Severity: Warning

Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests

Filename: helpers/my_audit_helper.php

Line Number: 176

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 1034
Function: getPubMedXML

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3152
Function: GetPubMedArticleOutput_2016

File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

Correlation Between Postoperative Central Corneal Thickness and Endothelial Damage After Cataract Surgery by Phacoemulsification. | LitMetric

AI Article Synopsis

  • The study aimed to investigate the relationship between corneal swelling (edema) and the loss of endothelial cells after cataract surgery using microcoaxial phacoemulsification in 85 patients.
  • Data was collected at various time points post-surgery, showing that significant corneal swelling was linked to greater endothelial cell loss, particularly noted 4 days after surgery.
  • Results suggest that measuring corneal thickness after surgery could serve as an indicator of potential endothelial damage, highlighting its importance in postoperative assessments.

Article Abstract

Purpose: To study the correlation between postoperative corneal edema and endothelial cell loss after cataract surgery by microcoaxial phacoemulsification.

Methods: Eighty-five eyes of 85 consecutive patients with mild cataract (up to C5, N4, and P5: per LOCS III classification) were included in a prospective study from September 2014 to November 2014. Eighty-five eyes were necessary to obtain a precision of 0.15 for computation of the Pearson correlation coefficient. Pachymetry and endothelial cell density measurements were taken preoperatively, 2 hours after surgery, and 4 days, 15 days, and 1 month after surgery using CEM-530 noncontact specular microscopy (Nidek CO Ltd, Japan). Every surgery was performed using the Stellaris device (Bausch & Lomb, Bridgewater, NJ) in a microcoaxial mode with 2.2-mm incisions.

Results: Mean age was 73 ± 2.1 years, with 41 women (48%) and 44 men (52%). The mean surgical time was 8 ± 5.5 minutes, and the mean effective phacoemulsification time was 7 ± 3.7 seconds. Mean central corneal thickness augmentation was 46.68 ± 10 μm (8.39%) 2 hours after surgery, 10 ± 18 μm (1.8%) 4 days after surgery, and only 0.76 ± 11.4 μm (0.1%) 15 days after surgery. Mean endothelial cell loss was 3.0 ± 1.5% at 2 hours, 9.0 ± 3.3% at D4, 10 ± 4.6% at D15, and 11 ± 4.7% at 1 month. At D4, significant endothelial loss (>15%) was mostly related to significant immediate corneal edema (>15%), whereas low postoperative edema (<5%) did not lead to significant endothelial loss (loss <5%). At D15 and D30, endothelial cell loss seemed to be closely correlated with immediate postoperative edema (Pearson correlation coefficient between central corneal edema at H2 and endothelial cells loss at 1 month: r = 0.4, P < 0.0001).

Conclusions: Postoperative corneal thickness measurement may therefore become a marker of endothelial damage after phacoemulsification.

Download full-text PDF

Source
http://dx.doi.org/10.1097/ICO.0000000000001502DOI Listing

Publication Analysis

Top Keywords

endothelial cell
12
correlation postoperative
8
central corneal
8
corneal thickness
8
surgery
8
cataract surgery
8
corneal edema
8
cell loss
8
eighty-five eyes
8
hours surgery
8

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!