This case study reports the successful implantation of the Xen ab interno gel stent in a 44-year-old man with refractory chronic open-angle glaucoma. The patient had multiple unsuccessful filtration surgeries including a trabeculectomy and 2 Ahmed glaucoma valves placed superotemporally and inferonasally oculus dexter. The patients intraocular pressure was reduced from 29 mm Hg preoperatively to 17 mm Hg 1 year after surgery, without any ocular complications. The Xen gel stent may be considered as a possible intervention to lower intraocular pressure in patients with refractory glaucoma, despite previous filtration surgeries if the superonasal conjunctiva is spared and healthy.
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http://dx.doi.org/10.1097/IJG.0000000000000864 | DOI Listing |
Korean J Ophthalmol
December 2024
Department of Ophthalmology, Institute of Vision Research, Severance Eye Hospital, Yonsei University College of Medicine, South Korea.
Purpose: To compare the clinical outcomes of Xen 45 gel stent implantation surgery (Ab externo, open conjunctiva) with those of trabeculectomy.
Method: We retrospectively reviewed electronic medical record of 57patients (62eyes) treated with Xen implantation surgery (ab externo, open conjunctiva approach) between April 1st, 2021 and July 31st, 2023 by the same surgeon. Preoperative clinical data including intraocular pressure, the number of glaucoma medications, visual acuity were collected from 1 day to 12 months postoperatively.
Materials (Basel)
November 2024
School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, China.
With the continuous progress of biomedical technology, biomaterial coatings play an important role in improving the performance of medical devices and promoting tissue repair and regeneration. The application of natural medicine to biological materials has become a hot topic due to its diverse biological activity, low toxicity, and wide range of sources. This article introduces the definition and classification of natural medicines, lists some common natural medicines, such as curcumin, allicin, chitosan, tea polyphenols, etc.
View Article and Find Full Text PDFJ Curr Glaucoma Pract
October 2024
Department of Ophthalmology, Hospital of San Severino Marche, AV3- Asur Marche, Macerata, Italy.
Ocul Immunol Inflamm
November 2024
Centre for Ophthalmology, University Hospital Tuebingen, Tuebingen, Germany.
Purpose: To investigate the long-term outcomes of XEN-45 implantation for glaucoma secondary to Fuchs uveitis syndrome (FUS), juvenile idiopathic arthritis (JIA)-related anterior uveitis and intermediate uveitis (IU).
Methods: This retrospective study evaluated 19 eyes with FUS, 10 eyes with JIA, and nine eyes with IU that underwent XEN-45 Gel Stent implantation. The primary outcome measure was 3-year surgical success, defined as a ≥20% reduction in intraocular pressure (IOP), with a target IOP of 6-21 mmHg.
Int Ophthalmol
November 2024
Department of Ophthalmology, Zhongda Hospital Affiliated to Southeast University, Nanjing, China.
Objective: To assess the efficacy of XEN gel stent implantation combined with mitomycin C (MMC) injection in controlling intraocular pressure (IOP) and the dosage of postoperative medication for open-angle glaucoma (OAG) patients.
Methods: The PubMed, Embase, Cochrane Library, and Science Direct databases were searched from inception to August 2022 without any language restriction. All studies that compared IOP and the dose of medication before and after XEN gel stent implantation and MMC injection for OAG patients were included.
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