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Molecular Detection and Phylogenetic Analysis of Orf Virus From Dermatological Lesions in the Teats of Goats.
Vet Med Sci
January 2025
Department of Virology, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur, Türkiye.
Background: The orf virus (ORFV) is a viral pathogen that primarily causes contagious ecthyma in humans and different ruminants. The infection, which is common worldwide, causes large-scale economic losses to animal breeders.
Objective And Methods: In this study, tissue samples collected from eight randomly selected goats with dermatological lesions on the teats were examined in different goat herds.
[Not Available].
Dermatologie (Heidelb)
January 2025
Zentrum für Dermatologie, Allergologie und Dermatochirurgie, Helios Universitätsklinikum Wuppertal, Wuppertal, Deutschland.
Phylogenetic analysis reveals genetic characteristics of orf virus F1L and B2L genes in the Fujian province.
Am J Vet Res
January 2025
Institute of Animal Husbandry and Veterinary Medicine, Fujian Academy of Agricultural Sciences, Fuzhou, China.
Objective: This study investigates the molecular epidemiology of orf virus (ORFV) in the Fujian province in 2024, with the goal of gaining insights that can enhance disease prevention and control strategies.
Methods: This experimental study was conducted from January 2024 through March 2024. The samples, showing suspected orf lesions, tested positive for ORFV via PCR.
Preparation and characterization of a mouse polyclonal antibody against the truncated ORFV113 recombinant protein of Orf virus.
Vet J
December 2024
Department of Veterinary Medicine, College of Animal Science, Guizhou University, Guiyang 550025, China. Electronic address:
Orf is a contagious zoonotic disease caused by Orf virus (ORFV), posing a threat to both animal and human health. The ORFV113 gene, located in the terminal variable region of the ORFV genome, has been demonstrated as a significant virulence gene, but its function remains largely unknown. In the study, we first amplified the truncated version of the ORFV113 gene (ORFV113t) by removing its transmembrane domain at the 5' end.
View Article and Find Full Text PDFPathogenicity and phylogenetic analysis of ovine contagious ecthyma virus isolated during a sheeppox outbreak in Morocco.
Microb Pathog
December 2024
Research and Development, MCI Santé Animale, Lot. 157, Z. I., Sud-Ouest (ERAC) B.P: 278, Mohammedia, 28810, Morocco. Electronic address:
Article Synopsis
- Contagious ecthyma (CE), also known as ORF, is a viral skin disease affecting humans and various animals, including sheep and goats.
- A study investigating an outbreak of sheeppox and ORF in Northwest Morocco identified skin lesions in affected sheep and confirmed ORF through PCR testing.
- This research marks the first detection of ORF in Morocco, highlighting a potential health risk for humans and animals alike.
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