Objectives: In recent years the impact of the left atrium (LA) has become more evident in different cardiovascular pathologies. We aim to provide LA parameters in healthy volunteers for cardiovascular magnetic resonance (CMR) using a fast approach.
Design: We analyzed 203 healthy volunteers (mean age 44.6 years (y), range 19y-76y) at 1.5 and 3.0 Tesla (T) using steady-state free precession (SSFP) cine in routine long axis view. Left atrial enddiastolic volume (LA-EDV), endsystolic volume (LA-ESV), stroke volume (LA-SV) and ejection fraction (LA-EF) were quantified and indexed to body-surface-area (BSA). Dependency on age and sex was analyzed.
Results: 21 subjects had to be excluded. In the remaining, there was no significant difference between 1.5 T and 3.0 T. Absolut LA-EDV and LA-ESV were larger in men than in women (LA-EDV: male 70 ± 19 ml vs. female 61 ± 16 ml (p = .001); LA-ESV: male 24 ± 9 ml vs. female 21 ± 8 ml (p = .01)). These differences disappeared after indexing to BSA (LA-EDV/BSA: male 34 ± 10 ml/m vs. female 33 ± 9 ml/m (p = .65) and LA-ESV/BSA: male 12 ± 4 ml/m vs. female 11 ± 4 ml/m (p = .71)). LA-EDV/BSA decreased with older age.
Conclusions: Reference values for LA size and function based on a fast approach are provided. LA size decreases with older age. Normalization to body size overcomes sex-dependency. Reports should be related to body size.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/14017431.2017.1423107 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Atrial Cardiomyopathy: From Diagnosis to Treatment.
Rev Cardiovasc Med
January 2025
Department of Cardiology, Renmin Hospital of Wuhan University, 430060 Wuhan, Hubei, China.
With a better understanding of the susceptibility to atrial fibrillation (AF) and the thrombogenicity of the left atrium, the concept of atrial cardiomyopathy (ACM) has emerged. The conventional viewpoint holds that AF-associated hemodynamic disturbances and thrombus formation in the left atrial appendage are the primary causes of cardiogenic embolism events. However, substantial evidence suggests that the relationship between cardiogenic embolism and AF is not so absolute, and that ACM may be an important, underestimated contributor to cardiogenic embolism events.
View Article and Find Full Text PDFA Rare Case of a Cardiac Papillary Fibroelastoma Arising in the Right Atrial Septum and Resected via Minimally Invasive Cardiac Surgery.
Cureus
December 2024
Second Department of Surgery, Faculty of Medicine, Yamagata University, Yamagata, JPN.
Papillary fibroelastomas (PFEs) are rare, benign, primary cardiac tumors, typically found on the valve surfaces and more commonly on the left side of the heart, with occurrences in the right atrium even rarer. In this case, a highly mobile tumor was incidentally detected in the right atrium of an 83-year-old woman with advanced right lung cancer during preoperative transthoracic echocardiography and magnetic resonance imaging. Although the patient was asymptomatic and of advanced age, the tumor's high mobility warranted resection.
View Article and Find Full Text PDFComparative analysis of left atrial size and appendage morphology in paroxysmal and persistent atrial fibrillation patients.
J Arrhythm
February 2025
Heart Center Munich-Bogenhausen, Department of Cardiology and Internal Intensive Care Medicine Munich Hospital Bogenhausen, Munich Municipal Hospital Group Munich Germany.
Purpose: Pulmonary vein isolation (PVI) is effective in treating atrial fibrillation (AF), but outcomes are worse for persistent AF (persAF) patients than paroxysmal AF (PAF) patients. The study aimed to identify differences in left atrial (LA) and left atrial appendage (LAA) anatomy in different AF types.
Methods: In a single-center observational study, a blinded retrospective analysis of preprocedural cardiac computed tomography angiography (CCTA) images was performed.
Dispersion-based cognitive intra-individual variability in former American football players: Association with traumatic encephalopathy syndrome, repetitive head impacts, and biomarkers.
Clin Neuropsychol
January 2025
Department of Neurology, Boston University Alzheimer's Disease Research Center, Boston University CTE Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.
Exposure to repetitive head impacts (RHI), such as those experienced in American football, is linked to cognitive dysfunction later in life. Traumatic encephalopathy syndrome (TES) is a proposed clinical syndrome thought to be linked to neuropath-ology of chronic traumatic encephalopathy (CTE), a condition associated with RHI from football. Cognitive intra-individual variability (d-CIIV) measures test-score dispersion, indicating cognitive dysfunction.
View Article and Find Full Text PDFCurrent Diagnosis and Therapeutic Approach of Functional Mitral Regurgitation.
Acta Med Indones
October 2024
Department of Cardiology and Vascular Medicine Universitas Indonesia - Universitas Indonesia Hospital, Depok, Indonesia.
Functional mitral regurgitation is characterized by normal structures of the mitral valve and chordae tendinea, but the regurgitation occurs due to geometric changes in the left atrium and left ventricle. This condition can contribute to heart failure progression and lead to a poor prognosis. Functional mitral regurgitation is found in approximately one-third of patients with heart failure with a decreased ejection fraction.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!