The nickel-catalyzed decarbonylation of unstrained diaryl ketones has been developed. The reaction is catalyzed by a combination of Ni(cod) and an electron-rich N-heterocyclic carbene ligand. High functional group tolerance and excellent yields (up to 98%) are observed. This strategy provides an alternative and versatile approach to construct biaryls using an inexpensive nickel catalyst.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/jacs.7b11591 | DOI Listing |
Publication Analysis
Top Keywords
decarbonylation unstrained
8
directed decarbonylation
4
unstrained aryl
4
aryl ketones
4
ketones nickel-catalyzed
4
nickel-catalyzed c-c
4
c-c bond
4
bond cleavage
4
cleavage nickel-catalyzed
4
nickel-catalyzed decarbonylation
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!