TiO₂ nanotubes (TNT) formation is beneficial for improving bone cell-material interaction and drug delivery for Ti dental implants. Among the natural drugs to be installed in TNT, selected propolis has antibacterial and anti-inflammatory properties. It is a resinous natural product which is collected by the honeybees from the various types of plants with their salivary enzymes. This study concludes that TNT loaded with a propolis (PL-TNT-Ti) dental implant has the ability to improve osseointegration. The propolis particles were embedded within the TNT or adhered to the top. In a cytotoxicity test using osteoblast, PL-TNT-Ti group exhibited an increased cell proliferation and differentiation. A Sprague Dawley rat mandibular model was used to evaluate the osseointegration and bone bonding of TNT or PL-TNT-Ti. From the µ-CT and hematoxylin and eosin (HE) histological results after implantation at 1 and 4 weeks to rat mandibular, an increase in the extent of new bone formation and mineral density around the PL-TNT-Ti implant was confirmed. The Masson's trichrome staining showed the expression of well-formed collagenous for bone formation on the PL-TNT-Ti. Immunohistochemistry staining indicate that bone morphogenetic proteins (BMP-2 and BMP-7) around the PL-TNT-Ti increased the expression of collagen fibers and of osteogenic differentiation whereas the expression of inflammatory cytokine such as interleukin-1 beta (IL-1ß) and tumor necrosis factor-alpha (TNF-α) is decreased.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793559 | PMC |
| http://dx.doi.org/10.3390/ma11010061 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Strength and Poisson's ratio of fused filament fabrication parts made from carbon filler enhanced PEEK compounds at elevated temperatures.
Sci Rep
December 2024
School of Electrical Engineering, Aalto University, P.O. Box 15500, Aalto, FI-00076, Finland.
Engineering plastics are finding widespread applications across a broad temperature spectrum, with additive manufacturing (AM) having now become commonplace for producing aerospace-grade components from polymers. However, there is limited data available on the behavior of plastic AM parts exposed to elevated temperatures. This study focuses on investigating the tensile strength, tensile modulus and Poisson's ratio of parts manufactured using fused filament fabrication (FFF) and polyetheretherketone (PEEK) plastics doped with two additives: short carbon fibers (SCFs) and multi-wall carbon nanotubes (MWCNTs).
View Article and Find Full Text PDFA Janus Separator Regulating Zinc Deposition Behavior Synergistically by Cellulose and ZrO Nanoparticles Toward High-Performance Aqueous Zinc-Ion Batteries.
Small
December 2024
Songshan Lake Materials Laboratory (SLAB), Dongguan, 523808, P. R. China.
Aqueous zinc-ion batteries (AZIBs) stand out among many energy storage systems due to their many merits, and it's expected to become an alternative to the prevailing alkali metal ion batteries. Nevertheless, the cumbersome manufacturing process and the high cost of conventional separators make them unfavorable for large-scale applications. Herein, inspired by the unique nature of cellulose and ZrO, a Janus cellulose fiber (CF)/polyvinyl alcohol (PVA)/ZrO separator is prepared via the vacuum filtration method.
View Article and Find Full Text PDFFacile Preparation of Carbon Nanotube-Based Skin-Like Pressure Sensors.
Small
December 2024
Department of Chemistry & Chemical Biology and the Brockhouse Institute for Materials Research, McMaster University, 1280 Main St. W., Hamilton, ON, L8S 4M1, Canada.
Flexible sensors have garnered significant interest for their potential to monitor human activities and provide valuable feedback for healthcare purposes. Single-walled carbon nanotubes (SWNTs) are promising materials for these applications but suffer from issues of poor purity and solubility. Dispersing SWNTs with conjugated polymers (CPs) enhances solution processability, yet the polymer sidechains can insulate the SWNTs, limiting the sensor's operating voltage.
View Article and Find Full Text PDFResolving the Kinetics of Single-Walled Carbon Nanotube-Polyester Polyurethane Nanoparticle Conjugate Fluorescence Sensors toward Polymer Degrading Enzymes.
Nano Lett
December 2024
Department of Chemical and Biological Engineering, Iowa State University, Ames, Iowa 50011, United States.
Single-walled carbon nanotubes (SWCNTs) are fluorescent materials that have been developed as sensors for measuring the activities of enzymes. However, most sensors to date rely on end-point measurement and empirical functions to correlate enzyme concentrations with fluorescence responses. Less emphasis is put on analyzing time-dependent fluorescence responses and their connections with enzymatic kinetics.
View Article and Find Full Text PDFUnderstanding the Effect of Electron Irradiation on WS Nanotube Devices to Improve Prototyping Routines.
ACS Appl Electron Mater
December 2024
CEITEC, Brno University of Technology, Purkyňova 123, 61200 Brno, Czech Republic.
To satisfy the needs of the current technological world that demands high performance and efficiency, a deep understanding of the whole fabrication process of electronic devices based on low-dimensional materials is necessary for rapid prototyping of devices. The fabrication processes of such nanoscale devices often include exposure to an electron beam. A field effect transistor (FET) is a core device in current computation technology, and FET configuration is also commonly used for extraction of electronic properties of low-dimensional materials.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!