We report a case of a 39-year-old woman who died of fulminant pulmonary thromboembolism (PE). Autopsy showed classical findings of fulminant PE with occlusion of the bilateral main stem pulmonary arteries. Ancillary testing revealed inherited thrombophilia (Prothrombin 20,210 G > A and MTHFR 677 C > T mutation). Pre-autopsy postmortem computed tomography was used to test whether virtual imaging studies alone (virtual autopsy) would be sufficient to detect PE. Our studies show that computed tomography (CT) can differentiate antemortem clots from a postmortem clot in certain cases, particularly when combined with magnetic resonance imaging (MRI), which is superior in the assessment of soft tissue. We show that postmortem CT and MRI can aid in the diagnosis of pulmonary embolism by virtual autopsy, especially when used in conjunction.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s12024-017-9940-z | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Fatal acute pulmonary embolism following endoscopic cyanoacrylate injection for gastric fundal varices.
Acta Gastroenterol Belg
January 2025
Department of gastroenterology, Ghent University Hospital, Ghent, Belgium.
Acute gastric variceal bleeding is a rare but serious complication of portal hypertension. Initial therapy for bleeding gastric varices focuses on acute hemostasis. In this regard, endoscopic cyanoacrylate injection (ECI) is the first-line approach.
View Article and Find Full Text PDFThe Use of Remote Learning Techniques for Pediatric Cardiopulmonary Resuscitation Simulation Highlighting the Intersection Between Pediatric Advanced Life Support (PALS) and Advanced Cardiac Life Support (ACLS) Pathways.
Cureus
December 2024
Department of Pediatrics/Division of Hospital Medicine, Children's National Hospital, Washington, DC, USA.
Introduction: Medical simulation education has expanded in the remote learning sphere, providing educational opportunities to under-resourced areas and the ability to engage learners limited by time or geographic location. Pediatric resuscitation training has historically been in-person relying on Pediatric Advanced Life Support (PALS) algorithms, yet many pediatric providers are often faced with treating adult or adult-sized patients. Our goal was to develop a tele-simulation remote learning module highlighting possible diagnoses and scenarios that require adult treatment-minded approaches for the pediatric clinician, including the use of Advanced Cardiac Life Support (ACLS) algorithms.
View Article and Find Full Text PDFVentilation/Perfusion Mismatch in Pulmonary Vein Stenosis Secondary to Atrial Fibrillation Ablation.
Asia Ocean J Nucl Med Biol
January 2025
Department of Radiology, Tokushima University Hospital, Tokushima City, Japan.
We present two patients with a history of paroxysmal atrial fibrillation who developed pulmonary vein stenosis (PVS) following atrial fibrillation (AF) ablation. Case 1 involved a female patient in her 50s who was asymptomatic for pulmonary symptoms but was found to have a high degree of left superior PVS 15 months after AF ablation. This was demonstrated using contrast-enhanced computed tomography (CE-CT) and supported by findings of perfusion defects on ventilation-perfusion (V/Q) scan.
View Article and Find Full Text PDFHow necessary it is to perform a ventilation scan in patients with a history of COVID-19 to rule out pulmonary thromboembolism?
Asia Ocean J Nucl Med Biol
January 2025
Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Objectives: This study evaluated the necessity of a ventilation scan in patients suspected of PE with a history of COVID-19 infection.
Methods: This was a cross-sectional study of patients with PCR-confirmed COVID-19 and suspected PE at a tertiary care hospital in 2020. They underwent ventilation/perfusion (V/Q) scintigraphy using single-photon emission computed tomography/computed tomography (SPECT/CT) and CT scans with or without contrast.
Role of echocardiographic indicators of right ventricular dysfunction in prediction of 30-day mortality in non-high-risk patients with acute pulmonary embolism within different variants of Bova score.
Kardiol Pol
January 2025
1st Department of Cardiology, Interventional Electrocardiology and Arterial Hypertension, Jagiellonian University Medical College, Kraków, Poland.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!