The purpose of this research was to determine if bracing altered muscle firing amplitude, duration, or timing, creating improved dynamic stability. We hypothesized that a derotational knee brace improved the stability of an ACL deficient knee by augmenting limb proprioception, causing hamstring muscles to increase in activity and/or to contract earlier during a side-step cut. Ten subjects with documented unilateral isolated ACL deficient knees and five normal controls participated. A strap dominant brace (Lenox Hill, Lenox Hill Brace, Inc., Long Island City, NY) and a shell dominant brace (CTi, Innovation Sports, Irvine, CA) were selected for study. Using footswitches and dynamic EMG, we tested each subject during performance of a side-step cutting maneuver. Subjects completed 15 trials: 5 without bracing, 5 with the strap dominant brace, and 5 with the shell dominant brace. Normals cut 10 times each on their dominant limb. In swing phase, subjects had 38% more and 32% higher lateral hamstring EMG activity than normals; in stance phase, subjects had less quadriceps and gastrocnemius activity but more medial hamstring activity. When braced during stance phase, the ACL deficient legs demonstrated a further reduction of 18% in quadriceps total activity and 14% in peak activity compared to the unbraced situation. The hamstrings showed a concomitant decrease of 18% in total activity. No timing differences were noted between the braced and unbraced conditions during swing or stance phase.(ABSTRACT TRUNCATED AT 250 WORDS)
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http://dx.doi.org/10.1177/036354658901700106 | DOI Listing |
Skeletal Radiol
December 2024
Department of Clinical Genomics, Mayo Clinic, 13400 East Shea Blvd, Scottsdale, AZ, 85259, USA.
COL9A1 encodes the alpha-1 chain of type IX collagen heterotrimer, which is a vital component of collagen fibrils in hyaline cartilage. There are preliminary lines of evidence suggesting that COL9A1 mutations may be associated with autosomal dominant multiple epiphyseal dysplasia (MED), a disorder affecting the epiphysis of long bones. With only 2 reported cases (both from the same family) of MED in autosomal dominant COL9A1-related disorders (MIM 614135) in the clinical scientific literature hitherto, the phenotype is poorly understood at present.
View Article and Find Full Text PDFJ Orthop Case Rep
July 2024
Department of Orthopaedics, Children's Hospital New Orleans, Louisiana, USA.
Introduction: Distal radius fractures account for nearly one-third of all pediatric fractures, making it among the most common of all pediatric fractures. Studies report that distal radius physeal arrest rates following trauma to the distal radius seem to occur in only about 5% of patients. Significant ulnar variance can develop leading to notable pain and limitations in function.
View Article and Find Full Text PDFInt J Mol Sci
May 2024
Department for Medical Chemistry, Biochemistry and Clinical Chemistry, Faculty of Medicine, University of Rijeka, Brace Branchetta 20, 51000 Rijeka, Croatia.
With projections suggesting an increase in the global use of neonicotinoids, contemporary farmers can get caught on the "pesticide treadmill", thus creating ecosystem side effects. The aim of this study was to investigate the sorption/desorption behavior of acetamiprid, imidacloprid, and thiacloprid that controls their availability to other fate-determining processes and thus could be useful in leveling the risk these insecticides or their structural analogues pose to the environment, animals, and human health. Sorption/desorption isotherms in four soils with different organic matter (OC) content were modelled by nonlinear equilibrium models: Freundlich's, Langmuir's, and Temkin's.
View Article and Find Full Text PDFDigit Biomark
April 2024
Department of Exercise Sciences, University of Auckland, Auckland, New Zealand.
Introduction: Wearable technology offers a promising solution to advance current rehabilitation strategies for post-operative orthopedic care. The aim of this study was to determine the level of agreement and concurrent validity of a smart knee brace compared to the gold standard measurement system GAITRite for assessing lower limb gait parameters.
Methods: Thirty-four healthy participants were fitted with the smart knee brace (Digital Knee) on their dominant limb.
J Mol Evol
October 2024
Evolutionary Bioinformatics Laboratory, Department of Crop Sciences and Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
The principle of continuity demands the existence of prior molecular states and common ancestors responsible for extant macromolecular structure. Here, we focus on the emergence and evolution of loop prototypes - the elemental architects of protein domain structure. Phylogenomic reconstruction spanning superkingdoms and viruses generated an evolutionary chronology of prototypes with six distinct evolutionary phases defining a most parsimonious evolutionary progression of cellular life.
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