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Strategies for implementing an electronic patient-reported outcomes-based symptom management program across six cancer centers.
BMC Health Serv Res
November 2024
Baptist Medical Center, 6019 Walnut Grove Rd, Memphis, TN, 38120, USA.
Article Synopsis
- Electronic patient-reported outcomes (ePROs) can enhance cancer patient care, but integrating them into clinical systems poses significant challenges, requiring technical resources, clinician and patient commitment, and institutional support.* -
- The SIMPRO Research Consortium created and implemented eSyM, an ePRO-based symptom management program across six cancer centers, tracking implementation methods and barriers through established frameworks and tools like REDCap.* -
- Out of 226 documented implementation strategies, 64 unique strategies were identified, with universal strategies that were consistently effective focusing on clinical preparation, training, and patient/clinician engagement being seen as particularly impactful.*
Integrating science into digital health workflows: A strategic approach for leaders.
Digit Health
November 2024
Fit Minded, Inc., Phoenix, Arizona, USA.
As the digital health industry becomes increasingly competitive, companies must integrate science cross-functionally to drive innovation and differentiation. However, many companies face significant challenges in effectively leveraging science across their organization. This commentary explores the common obstacles digital health companies encounter when integrating science, including limited C-suite understanding, siloed structures, resource constraints, change resistance, and value demonstration challenges.
View Article and Find Full Text PDFA plasma proteomic signature links secretome of senescent monocytes to aging- and obesity-related clinical outcomes in humans.
medRxiv
August 2024
Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Cellular senescence increases with age and contributes to age-related declines and pathologies. We identified circulating biomarkers of senescence associated with diverse clinical traits in humans to facilitate future non-invasive assessment of individual senescence burden and efficacy testing of novel senotherapeutics. Using a novel nanoparticle-based proteomic workflow, we profiled the senescence-associated secretory phenotype (SASP) in monocytes and examined these proteins in plasma samples (N = 1060) from the Baltimore Longitudinal Study of Aging (BLSA).
View Article and Find Full Text PDFMixed Reality in the Operating Room: An Initial Use in Frontal Sinus Setback in Gender-affirming Facial Surgery.
Plast Reconstr Surg Glob Open
June 2024
From the Department of Plastic Surgery, University of Pittsburgh Medical Center Pittsburgh, Pa.
Article Synopsis
- * The use of mixed reality (MR) technology, specifically Medivis's SurgicalAR with Microsoft HoloLens, allows surgeons to visualize and interact with 3D imaging of a patient's anatomy in real time.
- * In a study, the MR system successfully outlined patients' frontal sinuses with minimal differences compared to traditional 3D-printed guides, highlighting its potential as an effective imaging tool in gender-affirming surgeries.
Background: Electronic patient-reported outcome (ePRO)-based symptom management improves cancer patients' outcomes. However, implementation of ePROs is challenging, requiring technical resources for integration into clinical systems, substantial buy-in from clinicians and patients, novel workflows to support between-visit symptom management, and institutional investment.
Methods: The SIMPRO Research Consortium developed eSyM, an electronic health record-integrated, ePRO-based symptom management program for medical oncology and surgery patients and deployed it at six cancer centers between August 2019 and April 2022 in a type II hybrid effectiveness-implementation cluster randomized stepped-wedge study.
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