Xanthelasma palpebrarum is the most common cutaneous xanthoma, characterized by yellowish plaques over eyelids - most commonly, over the inner canthus of the upper lid. It is triggered by hyperlipidemia, thyroid dysfunction, and diabetes mellitus. Xanthelasma results from perivascular infiltration of mono- and multinucleated foam cells within lipid-laden cytoplasmic vacuoles in the superficial reticular dermis. Different modalities of treatment, such as simple surgical excision, cryotherapy, chemical peeling with trichloroacetic acid, radiofrequency, and laser, are used in the treatment of xanthelasma palpebrarum. A brief review of current treatment strategies is presented here.
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| http://dx.doi.org/10.2147/CCID.S130116 | DOI Listing |
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Treatment of Xanthelasma Palpebrarum Using Trichloroacetic Acid 80.
J Clin Aesthet Dermatol
November 2024
All authors are affiliated with the Institute of Cosmetic and Laser Surgery in Oakville, Ontario. Canada.
Objective: We sought to analyze the effectiveness, recurrence, safety, and patient satisfaction rates following xanthelasma palpebrarum (XP) treatment with trichloroacetic acid (TCA) 80%.
Methods: This was a retrospective review of patients treated with TCA 80% for XP between January 2012 and August 2022. A prospective telephone questionnaire was administered to the same patient population to evaluate recurrence, patient satisfaction, and side effects.
Effective treatment of xanthelasma palpebrarum using Er:YAG laser.
Lasers Med Sci
January 2025
Department of Plastic and Reconstructive Surgery, Korea University College of Medicine, Korea University Anam Hospital, Seoul, South Korea.
Xanthelasma palpebrarum (XP), characterized by soft, yellowish plaque primarily on the eyelids, is often associated with lipid metabolism disorders. XP can cause aesthetic concerns that affect social interactions and requires careful treatment evaluations due to potential complications and associations with systemic conditions. We aimed to assess the efficacy of and recurrence rates with erbium:yttrium aluminum garnet (Er:YAG) laser therapy in the treatment of XP.
View Article and Find Full Text PDFAssessment and Predictors of Metabolic Syndrome in Patients of Xanthelasma Palpebrarum: An Observational Study.
Dermatol Pract Concept
October 2024
Department of Dermatology, Venereology and Leprosy, Teerthanker Mahaveer Medical College and Research Centre, Moradabad, Uttar Pradesh, India.
Introduction: Xanthelasma palpebrarum is considered to be a cutaneous marker for cardiovascular diseases, and there is a known association with hypertension, insulin resistance, diabetes mellitus, obesity, and stroke.
Objectives: Our aim was to study the association and identify the predictors of metabolic syndrome in patients with xanthelasma palpebrarum.
Methods: An observational study was conducted on 55 patients in which patients of both sexes ages 20-70 years without any other skin condition were included after written informed consent.
Aesthetic Surgical Treatment of Large Xanthelasma palpebrarum.
Aesthetic Plast Surg
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Department of Plastic and Reconstructive Surgery, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui Province, People's Republic of China.
Background: Xanthelasma palpebrarum (XP) is a common eyelid condition. Various treatment modalities exist, each with its own merits and drawbacks. Managing larger lesions poses increased challenges.
View Article and Find Full Text PDFA scoring-based clinical grading model for xanthelasma palpebrarum: predicting treatment frequency and prognosis.
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Department of Plastic and Reconstructive Surgery, East Hospital, Affiliated to Tongji University, No. 150, Jimo Road, Pudong New District, Shanghai, China.
Article Synopsis
- Xanthelasma palpebrarum is a common skin condition characterized by yellowish lesions, and while there are treatment options, they often face issues with recurrence and frequency.
- Researchers created a clinical scoring system based on the local injection of pingyangmycin, aimed at predicting treatment outcomes for patients with this condition.
- The study analyzed 246 patient cases and identified key risk factors, using statistical models to validate a new grading system that has shown promise for improving treatment approaches in future clinical practice.
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