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Use of a Sugar Cross-Linked Collagen Membrane Offers Cell Exclusion and Ossification. | LitMetric

Use of a Sugar Cross-Linked Collagen Membrane Offers Cell Exclusion and Ossification.

Compend Contin Educ Dent

Chief Medical Officer and Co-owner, Datum Dental Ltd., Lod, Israel; Private Practice limited to Periodontics and Dental Implants, Ramat Hasharon, Israel.

Published: January 2018

Resorbable barrier membranes are advantageous for use in guided bone regeneration for treatment of peri-implant defects, eliminating the need for surgical re-entry. Ribose, a natural sugar-based material that has been used to cross-link collagen, is able to be utilized in high concentrations to extend barrier function for long periods without eliciting inflammation or foreign body reactions in situ. A unique finding with a ribose cross-linked collagen membrane is the in situ ossification of the material upon re-entry. This article presents two cases that clinically demonstrate the efficacy of a sugar cross-linked collagen membrane in peri-implant and site development type defects and suggest its ability to ossify and achieve bone regeneration.

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