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Did Primary Healthcare Patients in Riyadh Experience Their First Migraine Episodes After a Stressful Event, and What Triggers and Relievers Do They Commonly Report?
Cureus
November 2024
Family Medicine, Dar Al Uloom University, Riyadh, SAU.
Objective: This study aimed to investigate whether the first onset of migraine episodes among primary healthcare patients in Riyadh, Saudi Arabia, is preceded by a highly stressful event, as well as to identify common potential triggers and relievers reported by these patients.
Background: Migraine is a prevalent and debilitating neurological disorder. The pathophysiology of migraine involves complex interactions between genetic, neurological, and environmental factors, including the trigeminovascular system and neuropeptides such as calcitonin gene-related peptide (CGRP).
Male-female comparison of vasomotor effects of circulating hormones in human intracranial arteries.
J Headache Pain
December 2024
Department of Clinical Sciences, Faculty of Medicine, Lund University, Getingevagen 4, Lund, 22185, Sweden.
Background: The purpose of this study was to examine whether there are sex differences in vasomotor responses and receptor localization of hormones and neuropeptides with relevance to migraine (vasopressin, oxytocin, estrogen, progesterone, testosterone, amylin, adrenomedullin and calcitonin gene-related peptide (CGRP)) in human intracranial arteries.
Methods: Human cortical cerebral and middle meningeal arteries were used in this study. The tissues were removed in conjunction with neurosurgery and donated with consent.
[Joint guideline of the Headache Working Group of the Hungarian Headache Society (MFT) and the Hungarian Pain Society (MOFT) for the practical care of acute and chronic migraine].
Ideggyogy Sz
November 2024
Fejér Megyei Szent György Egyetemi Oktató Kórház, Neurológiai Osztály, Székesfehérvár.
Migraine is a disabling primary headache disorder that directly affects a significant proportion of the population. Despite its widespread prevalence, migraine remains under-diagnosed and under-treated. To support clinical decision-making, we convened a panel of experts to develop a clinical approach to the diagnosis and management of migraine.
View Article and Find Full Text PDFAlterations of white matter microstructure in migraine patients vary in the peri-ictal phases.
eNeuro
December 2024
Institute for Systems and Robotics and Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal.
Alterations in white matter (WM) microstructure are commonly found in migraine patients. Here, we employ a longitudinal study of episodic migraine without aura using diffusion MRI (dMRI) to investigate whether such WM microstructure alterations vary through the different phases of the pain cycle. Fourteen patients with episodic migraine without aura related with menstruation were scanned through four phases of their (spontaneous) migraine cycle (interictal, preictal, ictal and postictal).
View Article and Find Full Text PDFCycling sensitivity across migraine phases: A longitudinal case-control study.
Eur J Pain
January 2025
Department of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Background: Functional neuroimaging studies indicate that central transmission of trigeminal pain may commence up to 48 h prior to the onset of headache. Whether these cyclic changes are associated with somatosensory alteration remains incompletely understood.
Methods: The present study aimed to investigate the temporal progression of somatosensory alterations preceding the onset of a migraine attack.
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