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A safe-enhanced fully closed-loop artificial pancreas controller based on deep reinforcement learning.
PLoS One
January 2025
Institute of Visual Informatics, The National University of Malaysia (UKM), Bangi, Malaysia.
Patients with type 1 diabetes and their physicians have long desired a fully closed-loop artificial pancreas (AP) system that can alleviate the burden of blood glucose regulation. Although deep reinforcement learning (DRL) methods theoretically enable adaptive insulin dosing control, they face numerous challenges, including safety and training efficiency, which have hindered their clinical application. This paper proposes a safe and efficient adaptive insulin delivery controller based on DRL.
View Article and Find Full Text PDFBenchmarking antimicrobial use to antimicrobial resistance: a comparative study of two hospitals using current National Healthcare Safety Network (NHSN) metrics.
Infect Control Hosp Epidemiol
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Center for Health Equity and Innovation, Cook County Health, Chicago, IL, USA.
Objective: We aimed to determine whether benchmarking antimicrobial use (AU) to antimicrobial resistance (AR) using select AU/AR ratios is more informative than AU metrics in isolation.
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Pre-Radiation Targeted Therapy for Highly Selected Patients with Newly Diagnosed Glioblastoma: New Tricks for an Old Dog?
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Division of Neuro-Oncology, Department of Neurology, and the Herbert Irving Comprehensive Cancer Center, Columbia University Vagelos College of Physicians & Surgeons and New York-Presbyterian New York, NY, USA.
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JBJS Essent Surg Tech
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OhioHealth, Grant Medical Center, Columbus, OH.
Modern techniques of rib fracture fixation surgery follow the AO principles of fracture reduction, fixation, and appropriate soft tissue handling. Fixation techniques can be performed using anatomic reduction and rigid fixation, or bridge plate fixation for comminuted fractures. Anatomic and nonanatomic plates can be used, although titanium precontoured locking plates are the most commonly used.
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