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Combination Therapy with Baricitinib and Narrowband Ultraviolet B for Active Non-Segmental Vitiligo: A Retrospective Controlled Study.
Clin Cosmet Investig Dermatol
December 2024
Department of Dermatology, Air Force Medical Center, PLA, Beijing, People's Republic of China.
Background: Vitiligo is a chronic autoimmune disease manifested by depigmented patches of skin devoid of melanocytes. Baricitinib, a JAK inhibitor selectively targeting JAK1/2, has shown preliminary efficacy for vitiligo. We aimed to assess the efficacy and tolerability of combination therapy with baricitinib and narrowband UV-B (NB-UVB) to treat active nonsegmental vitiligo (NSV).
View Article and Find Full Text PDFPhototherapy as an alternative in the treatment of chronic spontaneous urticaria.
Front Allergy
November 2024
Allergy Unit, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Chronic spontaneous urticaria (CSU) is defined as the occurrence of hives, angioedema, or both, lasting for more than 6 weeks. The treatment is based on the use of antihistamines, omalizumab, and/or cyclosporine following a stepwise algorithm recommended by international guidelines with a high level of evidence. Nevertheless, management can be challenging as some patients do not respond to the suggested drugs or have difficulties accessing them for various reasons.
View Article and Find Full Text PDFA Retrospective Comparison Between Home and in-Office NB-UVB Efficacy for Patients With Mycosis Fungoides.
Photodermatol Photoimmunol Photomed
November 2024
Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Introduction: This study addresses the gap in research comparing the effectiveness between home and in-office narrowband ultraviolet B (NB-UVB) phototherapy for the treatment of mycosis fungoides (MF). Elderly and disabled patients with this condition disproportionally lack access to home units due to insurance denial.
Materials And Methods: A retrospective review included patients diagnosed with MF or Sezary syndrome who underwent either in-office or home UVB between 2016 and 2023.
A Systematic Review of Case Series and Clinical Trials Investigating Regenerative Medicine for the Treatment of Vitiligo.
J Cosmet Dermatol
November 2024
Department of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Aims And Objectives: The aim of this study is to examine the efficacy and safety of various regenerative medicine treatments, such as cell therapy, platelet-rich plasma (PRP), plasma-poor platelet (PPP), plasma-rich fibrin (PRF), mesenchymal stem cells, stromal vascular fraction (SVF), exosomes, adipose-derived stem cells (ADSC), and stem cell-conditioned media (SC-CM), for treating vitiligo.
Method: We conducted a thorough search of major databases such as PubMed, Scopus, and Web of Science, and selected 48 articles based on specific criteria. We used EndNote X8 and Google Sheets to review and extract data from the articles.
Efficacy and safety of narrowband ultraviolet B phototherapy for prurigo nodularis: a tertiary center experience.
An Bras Dermatol
January 2025
Department of Dermatology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey.
Article Synopsis
- Prurigo nodularis is a chronic skin condition that leads to intense itching, and narrowband-UVB (NB-UVB) phototherapy is a potential treatment, especially for patients with other health issues.
- In a study involving 30 patients, NB-UVB therapy resulted in complete response (80%) or partial response (20%) to treatment, with better outcomes for those with diffuse and central lesions.
- The study highlights the effectiveness and safety of NB-UVB for treating prurigo nodularis, but acknowledges its limitations, such as being conducted at a single center and having a retrospective design.
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