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| http://dx.doi.org/10.5056/jnm17083 | DOI Listing |
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A combination of carbonates and Opuntia ficus-indica extract protects esophageal cells against simulated acidic and non-acidic reflux in vitro.
Sci Rep
September 2024
Dr. Willmar Schwabe GmbH & Co. KG, Willmar-Schwabe-Str. 4, 76227, Karlsruhe, Germany.
Buffering of stomach acid by antacids is a well-established symptomatic therapy for heartburn. In addition, preparations from prickly pear (Opuntia ficus-indica) have been shown to reduce tissue damage in experimental gastritis models and to attenuate gastrointestinal discomfort in patients. Both active principles have been included in a fixed-combination product for symptomatic treatment of heartburn containing carbonate antacids (CaCO3 and MgCO3) and an extract from Opuntia ficus-indica cladodes.
View Article and Find Full Text PDFCharacteristics of symptomatic belching in patients with belching disorder and patients who exhibit gastroesophageal reflux disease with belching.
J Neurogastroenterol Motil
April 2021
Institute for Digestive Research, Digestive Disease Center Soonchunhyang University College of Medicine, Seoul, Korea.
Background/aims: Belching disorder (BD) is clinically distinct from gastroesophageal reflux disease (GERD) with belching. Supragastric belching (SGB) is closely associated with reflux episodes. This study investigates belch characteristics in association with reflux, compared between patients with BD and those who had GERD with belching.
View Article and Find Full Text PDFEsophageal Clearance in Laryngopharyngeal Reflux Disease: Correlation of Reflux Scintigraphy and 24-hour Impedance/pH in a Cohort of Refractory Symptomatic Patients.
Mol Imaging Radionucl Ther
February 2020
University of Notre Dame, CNI Molecular Imaging, Sydney, Australia
Objectives: The role of gastroesophageal reflux disease (GERD) in the aetiology of laryngopharyngeal reflux (LPR) is poorly understood and remains a controversial issue. The 24-hour impedance monitoring has shown promise in the evaluation of LPR but is problematic in pharyngeal recording. We have shown the utility of scintigraphic studies in the detection of LPR and lung aspiration of refluxate.
View Article and Find Full Text PDFSymptomatic Non-acidic Reflux in a Patient With Chronic Autoimmune Atrophic Gastritis Successfully Treated With Anti-reflux Surgery.
J Neurogastroenterol Motil
January 2018
Department of General and Digestive Surgery, Hospital Ramón y Cajal, Madrid, Spain.
Cardiorespiratory events in infants with gastroesophageal reflux symptoms: Is there any association?
Neurogastroenterol Motil
May 2018
Neonatology and Neonatal Intensive Care Unit, Department of Public Health and Pediatrics, University of Turin, Turin, Italy.
Background: Cardiorespiratory (CR) events (apnea, bradycardia, oxygen desaturation) and gastroesophageal reflux (GER) symptoms often coexist in infants admitted to Neonatal Intensive Care Unit, leading to over-prescription of drugs and delayed discharge. We aimed to evaluate the relationships between CR and GER events.
Methods: The temporal associations between CR and GER events were analyzed in symptomatic infants who underwent synchronized CR and pH-impedance monitoring.
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