Aim: To examine the effect of () eradication therapy on the extra-gastrointestinal factors in elderly patients by a before-after observational study in community medicine.
Methods: Medical records (1 May 2013-31 January 2014) of 130 patients who underwent eradication therapy with 2-year after-eradication observation in our institute were reviewed. Data on sex; age; body weight; body mass index (BMI); mean corpuscular volume (MCV); total protein; low-density lipoprotein cholesterol, triglyceride, haemoglobin A1c and haemoglobin levels and gastric hyperplastic polyps (GHPs) at eradication was extracted. Two-year after-eradication change in data was analysed by paired-sample -test; relationship between GHPs and subclinical iron deficiency anaemia (IDA) improvement was evaluated.
Results: The mean patient age (median, interquartile range) at eradication was 69.6 (71.5, 64-77) years. Paired-sample -tests showed that body weight, BMI and MCV increased by 0.52 kg ( = 0.018), 0.25 kg/m ( = 0.006) and 0.83 fL ( < 0.001), respectively. The nonparametric Mann-Whitney test showed no significant difference in the change rate of MCV after eradication between the groups with and without GHPs ( = 0.892).
Conclusion: eradication therapy prevented weight loss and subclinical IDA in elderly individuals. GHPs were not associated with subclinical IDA.
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| http://dx.doi.org/10.12998/wjcc.v5.i12.412 | DOI Listing |
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