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Effect of Artemisia annua on anticoccidial action, intestinal microbiota and metabolites of Hu lambs.
BMC Vet Res
January 2025
College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046, Henan, China.
Background: Coccidia are among the primary pathogens causing diarrhea and even fatalities in lambs. With the increasing use of chemical drugs to treat coccidiosis, the problem of drug resistance is becoming more and more threatening. Therefore, there is an urgent need to identify novel alternative drugs for the treatment of the lamb coccidia.
View Article and Find Full Text PDFMicrofluidic design and preparation of hydrogel microcapsules of Mesona chinensis polysaccharide: Characterization, pH-responsive behavior and gastrointestinal protection for Lactobacillus plantarum.
Int J Biol Macromol
January 2025
State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. Electronic address:
Probiotics have brought many health benefits to the human body. However, their viability during gastrointestinal transit is a concern. Therefore, this study selected Mesona chinensis polysaccharide (MCP), an edible natural polysaccharide, and constructed a new type of microcapsules using MCP as raw material to prepare cross-linked calcium ions through a microfluidic system as an ideal intestinal targeting carrier to achieve precise delivery of bioactive substances.
View Article and Find Full Text PDFOrally-Administrable Supramolecular Probiotic Capsules Enable Cooperative Colon-Targeted Inflammation Inhibition for Ameliorating Ulcerative Colitis.
Acta Biomater
January 2025
School of Life Sciences, Chongqing University, Chongqing, 400044, China.. Electronic address:
Ulcerative colitis (UC) is a prevalent gastrointestinal disease characterized by the chronical and refractory inflammation of colorectal mucosa and walls, which severely impairs overall well-being of individuals. Probiotics has shown tremendous promise for UC therapy due to its multifaceted mucosal barrier restoration and immunomodulation capabilities. Nevertheless, the successful administration of probiotics remains a clinical obstacle.
View Article and Find Full Text PDFImpact of probiotic treatment on clinical symptom reduction in schizophrenia: A systematic review and meta-analysis.
J Psychiatr Res
January 2025
Research Institute Hospital 12 de Octubre (imas12), Madrid, Spain; CIBERSAM-ISCIII (Biomedical Research Networking Centre for Mental Health/Carlos III Health Institute), Spain; Department of Legal Medicine, Psychiatry, and Pathology. Complutense University of Madrid, Madrid, Spain. Electronic address:
Introduction: Recent research has identified gut microbiota dysbiosis as a potential contributing factor in schizophrenia, leading to growing interest in exploring probiotics as a complementary approach to traditional antipsychotic treatments. This study aims to systematically evaluate the current evidence on the efficacy of probiotics in improving clinical symptoms of schizophrenia, offering a novel perspective into their potential role as an adjunctive strategy.
Methods: A systematic search was conducted to review randomized clinical trials, adhering to the PRISMA guidelines.
Probiotic active gel promotes diabetic wound healing through continuous local glucose consumption and antioxidant.
J Nanobiotechnology
January 2025
Shandong Key Laboratory of Proteins and Peptides Pharmaceutical Engineering, Shandong Universities Key Laboratory of Biological Medicine, School of Life Science and Technology, Shandong Second Medical University, 7166 # Baotong West Street, Weifang, Shandong, 261053, People's Republic of China.
Background: Diabetic foot ulcers (DFU) are severe complications of diabetes, posing significant health and societal challenges. Accumulation of reactive oxygen species (ROS) and elevated glucose levels are primary factors affecting diabetic wound healing. Achieving effective treatment by reducing ROS alone is challenging, as high glucose levels continuously drive ROS production.
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