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Effects of early-life malnutrition on neurodevelopment and neuropsychiatric disorders and the potential mechanisms. | LitMetric

Effects of early-life malnutrition on neurodevelopment and neuropsychiatric disorders and the potential mechanisms.

Prog Neuropsychopharmacol Biol Psychiatry

Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China; Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:

Published: April 2018

AI Article Synopsis

Article Abstract

Lines of evidence have demonstrated that early-life malnutrition is highly correlated with neurodevelopment and adulthood neuropsychiatric disorders, while some findings are conflicting with each other. In addition, the biological mechanisms are less investigated. We systematically reviewed the evidence linking early-life nutrition status with neurodevelopment and clinical observations in human and animal models. We summarized the effects of special nutritious on neuropsychiatric disorders and explored the underlying potential mechanisms. The further understanding of the biological regulation of early-life nutritional status on neurodevelopment might shed light on precision nutrition at an integrative systems biology framework.

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Source
http://dx.doi.org/10.1016/j.pnpbp.2017.12.016DOI Listing

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