Assessment of Total Antioxidant Capacity and Antimicrobial Activity of in Saliva of HIV-Infected Patients.

Objectives: The objectives of this study were to evaluate the antimicrobial activity and total antioxidant capacity (TAC) of licorice in Saliva of HIV/AIDS patients.

Materials And Methods: Saliva specimens were collected from 20 people living with HIV infection, with CD4 count <500 cells/mm from people infected with HIV/AIDS in Mangalore city, India. A combination of amoxicillin-clavulanic acid and nystatin was taken as the positive control and normal saline as negative control. Results were compared using one-way analysis of variance followed by Tukey's analysis in SPSS 19.

Results: The TAC was evaluated spectrophotometrically at 695nm using the phosphomolybdenum method. showed a statistically significant reduction ( < 0.05) in total count. The TAC of was found to be 4.467 mM/L.

Conclusions: extracts showed good anticandidal activity and also high antioxidant property which reduces the oxidative stress of HIV-infected people.