Introduction: Dental caries remains the most important dental health problem in developing countries. Application of varnish on tooth surfaces is shown to promote the uptake of firmly bound fluoride by enamel, which is considered important. Along with the incorporation of fluoride into the crystalline lattice, there is formation of calcium fluoride compounds on enamel.
Methodology: Seventy deciduous canines were covered with nail polish. A window measuring 4 mm × 4 mm was left on their buccal surface, These were randomly assigned to seven groups ( = 6): S: sound enamel not subjected to any regimen or treatment; N: negative control, subjected to the pH-cycling regimen without any treatment; D1 and D2: subjected to the pH-cycling regimen and treated two times daily with 1100 and 500 ppm dentifrice, respectively; VF: fluoride varnish (subjected to F-varnish before and in the middle of the pH-cycling regimen); and VF + D1 and VF + D2. After a period of 10 days, sectioning of teeth was done, and enamel demineralization was measured.
Results: The combination of dentifrice and varnish (groups VF + D1 and VF + D2) significantly reduced demineralization compared with the N group at all distances evaluated ( < 0.05), but the combination did not differ from the dentifrice groups at most distances from the surface ( > 0.05).
Conclusion: The results of this study suggest that the combination of F-varnish with dentifrices containing 500 or 1100 ppm F is not more effective in reducing demineralization in primary teeth than the isolated effect of dentifrice containing 1100 ppm.
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http://dx.doi.org/10.4103/jpbs.JPBS_121_17 | DOI Listing |
BMC Oral Health
January 2025
Department of Operative Dentistry, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
Background: This in vitro study evaluated the efficacy of professional and home-use fluoride regimens for protecting irradiated enamel, undergoing pH cycling resembling xerostomia.
Methods: Sixty human premolar teeth were irradiated with a total dose of 70 Gy and subsequently sectioned into 3 × 3 cm enamel slabs. These slabs were randomly distributed into five groups (n = 12 per group): professional-use groups received fluoride varnish either weekly (FV1) or biweekly (FV2); home-use groups applied 5000 ppm (FT5) or 1450 ppm (FT) fluoride toothpaste; and a control group (control) received no treatment.
Int J Clin Pediatr Dent
May 2024
Department of Public Health Dentistry, JSS Dental College and Hospital, Mysuru, Karnataka, India.
Aims And Background: The efficacy of self-assembling peptide P11-4 in combination with calcium-phosphate-based remineralization agents in remineralizing caries-like lesions in primary enamel was evaluated using a 21-day pH cycling experiment by Vickers microhardness [Vickers hardness number (VHN)] and scanning electron microscopy (SEM).
Materials And Methods: A total of 120 primary enamel samples were made to undergo a demineralization cycle to produce caries-like lesions. They were divided into six groups, namely negative control (NC), positive control (P11-4), and four interventional groups in which each of the following calcium-phosphate-based agents were used in combination with P11-4-calcium sucrose phosphate (CSP), bioactive glass (BG), casein phosphopeptides, and casein phosphopeptides with fluoride.
Oper Dent
May 2024
Frank Lippert, MSc, PhD, Department of Cariology and Operative Dentistry, Operative Dentistry and Dental Public Health, Indiana University School of Dentistry, Indianapolis, IN, USA.
Objectives: he aim of this in vitro study was to evaluate the effects of some bottled waters on fluoride toothpaste efficacy in enhancing caries lesion remineralization.
Methods: Early caries lesions were created in bovine enamel specimens and stratified into treatment groups based on Vickers surface microhardness (VHN). The present study followed a two (fluoride and fluoride-free toothpaste) by five (four bottled waters and tap water) factorial design.
Int Dent J
October 2024
Department of Pediatric Dentistry, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand. Electronic address:
Background: Fluoride gel treatment is not recommended for children < 6 years old due to its potential toxicity. Hence the aim of this study was to compare the effect of 1.23% acidulated-phosphate fluoride (APF) gel paint-on and the conventional tray application techniques on artificial, deciduous enamel carious lesions embedded on wearable appliances.
View Article and Find Full Text PDFBMC Oral Health
February 2024
Dental Biomaterials, Biomaterials Department, Faculty of Dentistry, Ain-Shams University, Organization of African unity street, El-Qobba Bridge, El-Weili, Cairo, Egypt.
Background: Several methods were introduced for enamel biomimetic remineralization that utilize a biomimetic analogue to interact and absorb bioavailable calcium and phosphate ions and induce crystal nucleation on demineralized enamel. Amelogenin is the most predominant enamel matrix protein that is involved in enamel biomineralization. It plays a major role in developing the enamel's hierarchical microstructure.
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