AI Article Synopsis

  • Partial X-irradiation of the hind part of a mouse body at a dose of 12 Gy causes significant negative impacts on clinical, hematologic, and immunological characteristics.
  • These harmful effects can be mitigated by administering a single dose of homologous immunoglobulin (200 mg/kg) via subcutaneous injection.
  • The immunoglobulin treatment should be given 2 hours post-irradiation for effective recovery.

Article Abstract

Partial X-irradiation of the hind part of mouse body with a dose of 12 Gy (LD15/30) was shown to produce a pronounced harmful effect on the clinico-hematologic and immuno-microbiological characteristics that could be coped with by a single subcutaneous injection of homologous immunoglobulin (200 mg/kg) 2 h following irradiation.

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