subspecies (SDSE) is an emerging pathogen in animals and humans. Herein, we describe two clinical swine cases of SDSE infection presenting with lameness, neurological signs, or sudden death. Pathological examination indicated suppurative arthritis, encephalitis, and multifocal abscesses in kidney and heart. The β-hemolytic colonies obtained from joint samples of each case were identified as SDSE. The two isolates had low minimum inhibitory concentrations for β-lactams, and they presented the same virulence gene profile (//pSTKP8). Molecular analysis by multilocus sequence typing identified the SDSE isolates from cases 1 and 2 as sequence types 315 and 252, respectively.
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http://dx.doi.org/10.4142/jvs.2018.19.2.313 | DOI Listing |
Infect Drug Resist
December 2024
Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, People's Republic of China.
Purpose: This study investigated the clinical relevance, pathogenic mechanisms, and neurological involvement of subspecies () and subspecies (), with a focus on a severe case of meningitis complicated by septic shock.
Patients And Methods: A systematic review of 19 cases of neurological infections caused by ( or ) from 1971 to 2023 was conducted, supplemented by a detailed case report. Data on patient demographics, predisposing factors, clinical manifestations, diagnostic procedures, treatment, and outcomes were analyzed.
mBio
November 2024
Laboratory for Molecular and Translational Human Infectious Diseases Research, Center for Infectious Diseases, Houston Methodist Research Institute, Houston, Texas, USA.
Unlabelled: subspecies (SDSE) is a Gram-positive bacterial pathogen that infects humans and is closely related to group A streptococcus (GAS). Compared with GAS, far less is known about SDSE pathobiology. Increased rates of invasive SDSE infections have recently been reported in many countries.
View Article and Find Full Text PDFIndian J Med Microbiol
December 2024
Department of Clinical Microbiology, Christian Medical College, Vellore, India. Electronic address:
Background: Streptococcus dysgalactiae subsp equisimilis (SDSE) is an emerging pathogen causing pharyngitis and post-streptococcal sequelae like S. pyogenes. SDSE was initially considered a commensal microorganism inhabiting the upper respiratory tract and skin.
View Article and Find Full Text PDFBMC Microbiol
September 2024
Department of Molecular Genetics and Infection Biology, University of Greifswald, Greifswald, Germany.
Background: Streptococcus dysgalactiae subspecies equisimilis (SDSE) is increasingly recognized as an emerging cause of invasive diseases including necrotizing soft tissue infections (NSTIs). In contrast to the closely related Streptococcus pyogenes, SDSE infections mainly affect older and comorbid patients. Biofilm formation has been demonstrated in soft tissue biopsies of S.
View Article and Find Full Text PDFEur J Clin Microbiol Infect Dis
August 2024
Department of Microbiology, Tokyo Medical University, Tokyo, Japan.
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