Regioselective alkali metal reduction of dibenzocyclooctadiene lignan derivatives, demethoxylation followed by dehalogenation.

Chem Cent J

State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Baijin Road, Guiyang, 550014, China.

Published: December 2017

The regioselective demethoxylation and dehalogenation of dihalogenated dibenzocyclooctadiene lignans derivatives were realized in a one-step reaction with excellent yields in the sodium and t-butanol reaction system.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745213PMC
http://dx.doi.org/10.1186/s13065-017-0368-zDOI Listing

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