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Introduction: Understanding how a research sample compares to the population from which it is drawn can help inform future recruitment planning. We compared the Wisconsin Alzheimer's Disease Research Center (WADRC) participant sample to the Wisconsin state population (WI-pop) on key demographic, social exposome, and vascular risk measures.
Methods: The WADRC sample included 930 participants.
Gut Microbiome Alterations Following Oral Serum-Derived Bovine Immunoglobulin Administration in the Management of Dysbiosis.
Cureus
December 2024
Psychiatry, Patton State Hospital, San Bernardino, USA.
Introduction: Inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) are chronic disorders of the gastrointestinal tract associated with gut microbiota dysbiosis and inflammation. Serum-derived bovine immunoglobulin (SBI) is used to manage IBS and IBD and has shown prebiotic-like effects in ex vivo models. Re-establishing a healthy gut microbiome with novel treatments like SBI could help treat the underlying causes of these diseases leading to higher and sustained patient response.
View Article and Find Full Text PDFPneumonia and Anemia in Rural Midwestern Missouri: A Retrospective Analysis.
Cureus
December 2024
Mathematics, Missouri Southern State University, Joplin, USA.
Introduction: Pneumonia and anemia are prevalent medical conditions with significant implications on patient health, resulting in numerous hospitalizations and deaths. Various studies have been done on the mortality rates of pneumonia and anemia individually. However, fewer describe the mortality of patients diagnosed with pneumonia superimposed on anemia.
View Article and Find Full Text PDFCoding intensity variation in Medicare Advantage.
Health Aff Sch
January 2025
Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, United States.
Enrollment in Medicare Advantage (MA) plans rose to over 50% of eligible Medicare patients in 2023. Payments to MA plans incorporate risk scores that are largely based on patient diagnoses from the prior year, which incentivizes MA plans to code diagnoses more intensively. We estimated coding inflation rates for individual MA contracts using a method that allows for differential selection into contracts based on patient health.
View Article and Find Full Text PDFThirty years later: the lingering effects of adolescent idiopathic scoliosis surgery with third-generation implants on quality of life.
Spine Deform
January 2025
Department of Spine Surgery, University Hospital of Vall d'Hebron, 129 Passeig Vall d´Hebron, 08035, Barcelona, Spain.
Purpose: To determine patient-reported clinical status in a cohort of patients operated on during adolescence for adolescent idiopathic scoliosis (AIS) using Cotrel-Dubousset instrumentation after a minimum follow-up (FU) of 25 years.
Methods: Multicentric cross-sectional observational study. We assessed the clinical status of patients using the lumbar-pain numeric rating scale (NRS), ODI, SRS-22r, SF-36, and EQ-5D-5L.
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