AI Article Synopsis
- The study aimed to assess the effectiveness of acetazolamide combined with various agents as intracanal medication in rat teeth that were reimplanted.
- A total of 100 Wistar rats were divided into five groups, each receiving different treatment combinations, and were analyzed at intervals of 30 and 60 days post-reimplantation.
- Results indicated that acetazolamide, particularly when combined with calcium hydroxide, could reduce root resorption and ankylosis compared to the control group, suggesting its potential as a beneficial treatment.
Article Abstract
Objective: The aim of this study was to evaluate the use of acetazolamide combined with different agents as intracanal medication in late reimplanted rat teeth.
Materials And Methods: In 100 Wistar rats, divided into 5 groups of 20, one of the following medications was used: Acetazolamide liquid (AL); AL with calcium hydroxide powder (ALHC); acetazolamide powder with AL; acetazolamide powder with physiological solution; and calcium hydroxide with physiological solution (control). At 30 and 60 days after reimplantation, the animals were sacrificed, tissues were processed, and cuts were stained with hematoxylin and eosin. An optical microscope was used to determine the following: percentage of inflammatory root resorption (RRI); percentage of substitute root resorption (RRS); and presence of ankylosis. The data obtained was submitted for statistical analysis.
Results: Group ALHC had a significantly higher RRS than the control group at 60 days ( = 0.01). Group AL showed significantly less ankylosis than the other groups, including the control, at 30 days. AL showed results similar to those of the control group with respect to RRS.
Conclusion: Acetazolamide has the potential to be an effective intracanal medication.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727723 | PMC |
| http://dx.doi.org/10.4103/ejd.ejd_191_17 | DOI Listing |
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