AI Article Synopsis
- The study aimed to compare cytoglobin (CYGB) levels in women with early-onset and late-onset preeclampsia to those with uncomplicated pregnancies.
- A total of 52 women with preeclampsia (26 with early-onset and 26 with late-onset) and 27 healthy pregnant women participated, and serum CYGB levels were measured.
- Results indicated that women with preeclampsia had significantly higher CYGB levels compared to the control group, but there was no significant difference in CYGB levels between early-onset and late-onset preeclampsia groups.
Article Abstract
Objective: To investigate cytoglobin levels in women with preeclampsia and women with uncomplicated pregnancies.
Materials And Methods: A cross-sectional study including 26 pregnant women complicated with early-onset preeclampsia (EO-PE) and 26 pregnant women complicated with late-onset preeclampsia (LO-PE) were recruited for the study group. Twenty-seven healthy pregnant women selected randomly were included in the control group. The serum CYGB concentrations were measured using an enzyme-linked immunosorbent assay.
Results: Gestational age at delivery and mean birth weight were significantly lower in the preeclampsia groups than in the control group and were found to be the lowest in the EO-PE group (p < .001). Serum CYGB levels were significantly higher in the EO-PE and LO-PE groups as compared with the control group (9.99 (6.08) ng/ml (EOPE), 10.04 (7.04) ng/ml (LOPE) versus 2.84 (0.82) ng/ml), (p < .001). However, a significant difference was not found between the EO-PE and LO-PE groups regarding CYGB levels (p = 1.000).
Conclusions: Serum CYGB levels were significantly higher in patients with EO-PE and LO-PE as compared to healthy pregnant women.
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| http://dx.doi.org/10.1080/14767058.2017.1421927 | DOI Listing |
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