Objective: To estimate the benefits of iterative prevalence surveys in detecting trends of hospital-acquired infections (HAIs).
Methods: On the basis of the French protocol for national prevalence studies, HAI data of 15 consecutive annual surveys performed at the same period by the same group of investigators was gathered in a single database to describe the trend of HAIs in a University Hospital over a 15-year period.
Results: A total of 20,401 patients were included. Overall, the prevalence of patients presenting with at least one HAI acquired in our University Hospital was 5.1% [95% CI, 4.8-5.4%]. The prevalence of HAIs and antimicrobial drug use significantly decreased over time (P<0.01).
Conclusion: Despite limitations, repeated prevalence surveys can be a useful tool for promoting control measures to better prevent HAIs.
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http://dx.doi.org/10.1016/j.medmal.2017.11.008 | DOI Listing |
Crit Care
January 2025
Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Background: Carbapenem-Resistant Gram-Negative Bacteria, including Carbapenem-Resistant Enterobacterales (CRE) and Carbapenem-Resistant Pseudomonas aeruginosa (CRPA), are common causes of infections in intensive care units (ICUs) in Italy.
Objective: This prospective observational study evaluated the epidemiology, management, microbiological characterization, and outcomes of hospital-acquired CRE or CRPA infections treated in selected ICUs in Italy.
Methods: The study included patients with hospital-acquired infections due to CRE and CRPA treated in 20 ICUs from June 2021 to February 2023.
Am J Transl Res
December 2024
Endoscopy Center of Gastroenterology Department, General Hospital of Central Theater Command Wuhan 430070, Hubei, China.
Objective: To evaluate the impact of optimized nursing management involving the Central Sterile Supply Department (CSSD) and Gastroenterology Department on sterilization processes, nurse well-being, and patient satisfaction.
Methods: This retrospective study analyzed data from 40 CSSD nurses and sterilization metrics for 1,017 gastroenterology instruments before and after implementing optimized management. The study included a control group (CG) prior to the intervention and an experimental group (EG) after.
J Patient Saf
January 2025
Mackenzie Health, Richmond Hill.
Background: Hospital-acquired pressure injuries (HAPIs) are common adverse events with large burdens on patients and health systems. In 2020, during the initial waves of the COVID-19 pandemic, the incidence of admitted patients with HAPIs of stage II and above in our health system rose from 2.92% to 3.
View Article and Find Full Text PDFmSphere
January 2025
Department of Food Science and Technology and Nebraska Food for Health Center, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Treatment with antibiotics is a major risk factor for infection, likely due to depletion of the gastrointestinal microbiota. Two microbiota-mediated mechanisms thought to limit colonization include the conversion of conjugated primary bile salts into secondary bile salts toxic to growth and competition between the microbiota and for limiting nutrients. Using a continuous flow model that simulates the nutrient conditions of the distal colon, we investigated how treatment with 6 clinically used antibiotics influenced susceptibility to infection in 12 different microbial communities cultivated from healthy individuals.
View Article and Find Full Text PDFInfect Prev Pract
March 2025
San Juan Bautista School of Medicine, Caguas, Puerto Rico.
Background: Mobile phones used by healthcare workers (HCWs) in hospitals are significant reservoirs of drug-resistant bacteria responsible for hospital-acquired infections (HAIs).
Aim: The objective of this study was to assess the level of contamination with such bacteria in outpatient clinics.
Methods: Swabs from 83 HCWs' mobile phones were processed using standard biochemical and enzymatic procedures to identify pathogenic bacteria.
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