Pyridostigmine for the Reversal of Severe Adverse Reactions to Botulinum Toxin in Children.

J Pediatr

Department of Otolaryngology-Head and Neck Surgery, Division of Pediatric Otolaryngology, Medical University of South Carolina, Charleston, SC; Department of Otolaryngology-Head and Neck Surgery, Evelyn Trammell Institute for Voice and Swallowing, Medical University of South Carolina, Charleston, SC.

Published: March 2018

Therapeutic botulinum toxin injections are commonly performed in pediatric otolaryngology. Aerodigestive complications from botulinum toxin injections, although rare, may be serious. Oral pyridostigmine is effective in the symptomatic treatment of these complications. We report 2 cases of aerodigestive complications arising from injection of botulinum toxin that were successfully treated with pyridostigmine.

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Source
http://dx.doi.org/10.1016/j.jpeds.2017.11.013DOI Listing

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