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Stem cell therapy in necrotizing enterocolitis: Current state and future directions. | LitMetric

Stem cell therapy in necrotizing enterocolitis: Current state and future directions.

Semin Pediatr Surg

Department of Surgery, Section of Pediatric Surgery, Indiana University School of Medicine, Riley Hospital for Children at IU Health, 705 Riley Hospital Dr. RI 2500, Indianapolis, Indiana 46202. Electronic address:

Published: February 2018

Stem cell therapy is a promising treatment modality for necrotizing enterocolitis. Among the many promising stem cells identified to date, it is likely that mesenchymal stem cells will be the most useful and practical cell-based therapies for this condition. Using acellular components such as exosomes or other paracrine mediators are promising as well. Multiple mechanisms are likely at play in the positive effects provided by these cells, and further research is underway to further elucidate these effects.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745058PMC
http://dx.doi.org/10.1053/j.sempedsurg.2017.11.011DOI Listing

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