John Collins Warren, the surgeon of Ether Day in 1846 at Massachusetts General Hospital, entered sulphuric ether into the nationally recognized Massachusetts pharmacopeia of 1808.
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| http://dx.doi.org/10.1016/j.janh.2017.09.007 | DOI Listing |
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Unexplained fever poses significant diagnostic challenges in resource-limited settings like Bamako, Mali, where overlapping endemic diseases include malaria, HIV/AIDS, yellow fever, typhoid, and others. This study aimed to elucidate the infectious etiologies of acute febrile illnesses in this context. Acute febrile patients of any age were enrolled after informed consent or assent.
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Global Alliance for Preventing Pandemics at the Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
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Surveillance and agnostic capture sequencing of samples from individuals with rash-associated illness in Mali indicates regional transmission of measles virus from West and Central Africa.
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Measles is vaccine-preventable extremely contagious disease caused by the measles virus. High vaccination coverage is needed to prevent outbreaks of disease. Although molecular surveillance of measles is critical to characterize outbreaks and track viral evolution, few whole-genome sequences of measles virus from West Africa are available despite continual outbreaks in the region.
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Department of Biology, Life Sciences Research Center, United States Air Force Academy, USAF Academy, CO 80840, USA.
Introduction: Wastewater surveillance is an important technique to monitor public health and is being studied extensively for pandemic prevention, force health protection and readiness, and as a potential early warning system for chem-bio defense. Wastewater surveillance has traditionally relied on techniques such as quantitative PCR or targeted sequencing, both of which are microbe- or disease-specific tools. Newer pan-viral metagenomics strategies may provide higher specificity for pathogens of interest, resulting in a lower false negative rate and reduced sequencing of undesired background nucleic acids.
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