AI Article Synopsis
- The study investigates the challenges of radiological evaluations after stereotactic-body-radiotherapy (SBRT) for non-small-cell lung carcinoma (NSCLC) using PET-CT scans.
- Eighteen NSCLC patients underwent PET-CT scans at various intervals before and after their SBRT treatment.
- Findings suggest that early PET-CT responses are linked to better local control of the cancer one year post-treatment, though results were inconsistent in some cases due to inflammation.
Article Abstract
Background/aim: Radiological evaluation after stereotactic-body-radiotherapy (SBRT) for non-small-cell lung carcinoma (NSCLC) is often difficult due to lung radiation-induced image modifications on computed tomographic (CT) scan. The aim of this study was to evaluate positron-emission tomography-computed tomography (PET-CT) using fluorodeoxyglucose after SBRT in primary lung cancer.
Patients And Methods: Eighteen patients with histologically proven NSCLC were treated with SBRT. All had PET-CT evaluations before treatment, at 2 to 3 months and at 1 year post SBRT during the follow-up.
Results: Early PET-CT in 12/18 patients who did not experience local failure did not show any progression. No conclusion could be drawn in four cases because early PET-CT was disturbed by inflammatory reaction. Early PET-CT was not predictive of late outcome for two patients, as it showed a significant response followed by disease progression on late evaluation.
Conclusion: Early PET response appears to correlate with local control at 1 year post SBRT.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892649 | PMC |
| http://dx.doi.org/10.21873/invivo.11213 | DOI Listing |
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