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Fexinidazole: A New Drug for African Sleeping Sickness on the Horizon. | LitMetric

Fexinidazole: A New Drug for African Sleeping Sickness on the Horizon.

Trends Parasitol

Northeastern University, Department of Chemistry and Chemical Biology, 102 Hurtig Hall, 360 Huntington Avenue, Boston, MA 02115, USA. Electronic address:

Published: March 2018

AI Article Synopsis

Article Abstract

Decades after the last new chemical entity was added to the pharmacopeia for human African trypanosomiasis (or sleeping sickness), orally dosed fexinidazole stands poised to replace the current treatment regimen for Trypanosoma brucei gambiense infections, following a positive Phase 2/3 clinical trial.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828866PMC
http://dx.doi.org/10.1016/j.pt.2017.12.002DOI Listing

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