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Introduction: Gigantomastia is a rare but not uncommon condition, and the most common surgical reduction procedure is by breast amputation with nipple-areolar grafting. Pedicle-based breast reduction is not commonly undertaken for such conditions.

Aim: This is a report of our experience in the use of an inferior-based pedicle for the reduction of gigantomastia.

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BRM: From Skin-Reducing Mastectomy to the New Concept of Breast Reshaping Mastectomy.

J Clin Med

February 2025

Plastic Surgery Unit, Department of Medical Biotechnology and Translational Medicine BIOMETRA, Humanitas Clinical and Research Hospital, Reconstructive and Aesthetic Plastic Surgery School, University of Milan, Via Manzoni 56, Rozzano, 20090 Milan, Italy.

Macromastia is a well-known issue in breast reconstruction. Skin-reducing mastectomy (SRM) was introduced as a skin-sparing mastectomy that utilizes a skin reduction pattern similar to breast reduction or breast lift surgery, specifically to manage hypertrophic and pendulous breasts. Over time, numerous authors have contributed to refining the SRM technique, leading to the development of various technical variants.

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Gestational gigantomastia or gravid macromastia is a rare condition presenting as incapacitating breast enlargement during pregnancy. It is physically and psychologically debilitating for the patient. Fewer than 100 cases have been published to date.

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Objectives: Symptomatic macromastia can lead to physical and psychosocial challenges, especially in younger patients. Here we aim to assess trends in the volume of pediatric reduction mammoplasties and their associated outcomes.

Methods: A retrospective review of the American College of Surgeons National Surgical Quality Improvement Program Pediatric (NSQIP-P) Participant Use Data File identified pediatric patients who underwent reduction mammoplasty from 2012 to 2021.

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Background: The amount of tissue resection, measured in weight per breast, in breast reduction surgery has been considered a potential risk factor for complications.

Objective: We aimed to evaluate the effect of removing >1000 g versus <1000 g of breast tissue in women with macromastia.

Methods: A systematic search was performed on Pubmed, Embase, and Cochrane in March 2024 for studies that compared resection weight >1000 g versus <1000 g in reduction mammoplasty.

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