AI Article Synopsis
- Thyroid hormones are crucial for the growth and function of all vertebrates, and their balance is maintained through the hypothalamic-pituitary-thyroid (HPT) axis.
- Nutrition, particularly the amount and type of protein consumed, significantly impacts the activity of the HPT axis and overall thyroid hormone levels.
- This review highlights how a low-protein diet or lack of essential amino acids can lead to thyroid hormone abnormalities, suggesting that understanding these relationships could improve nutrition-based treatments for thyroid issues and enhance animal breeding practices.
Article Abstract
Thyroid hormones (TH) are essential for the normal development and function of every vertebrate. The hypothalamic-pituitary-thyroid (HPT) axis is regulated to maintain euthyroid status. One of the most influential environmental factors that determines HPT axis activity is nutrition. Both food availability and substrate diversity affect thyroid hormone economy. The present paper aims to summarize literature data concerning the influence of the amount and the type of protein on thyroid axis activity. This review sheds light on the contribution of a low-protein diet or insufficient intake of essential amino acids to TH abnormalities. We believe that the knowledge of these dependencies could improve the results of nutritional interventions in thyroid axis disorders and enhance the efficiency of animal breeding.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793233 | PMC |
| http://dx.doi.org/10.3390/nu10010005 | DOI Listing |
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