Three-Dimensional Evaluation of Posterior Pole and Optic Nerve Head in Myopes with Glaucoma.

Sci Rep

Department of Ophthalmology, Seoul St. Mary's Hospital, College of medicine, The Catholic University of Korea, Seoul, Korea.

Published: December 2017

The degree of myopia is represented by a global index, such as refractive error or axial length. However, the progression of myopia mainly develops in the posterior eyeball. Therefore, it is reasonable to assume that the evaluation of myopia should be confined to the posterior segment, where most of the growth and lengthening occurs. Swept source optical coherence tomography software can reconstruct the scans to the coronal view of the posterior pole, which provides additional anterior-posterior depth (z axis in the Cartesian coordinates) that is not provided with the common fundus photograph. We deduced that the parameter of deepest point of the eyeball (DPE) as a surrogate for posterior pole configuration. Between myopes with and without normal tension glaucoma (NTG) with similar axial length, myopes with NTG had deeper and more distant location of the DPE from the optic disc. The difference of the DPE position between the myopes with and without NTG may have implications for the larger optic disc tilt and torsion characteristic of myopes with NTG. Furthermore, these data suggest that myopes with NTG go through excessive posterior scleral remodeling, which may result in vulnerable optic nerve head.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740057PMC
http://dx.doi.org/10.1038/s41598-017-18297-8DOI Listing

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