In most eukaryotes, including Saccharomyces cerevisiae, glycerophospholipids are the main membrane lipid constituents. Besides serving as general membrane 'building blocks', glycerophospholipids play an important role in determining the physical properties of the membrane, which are crucial for proper membrane function. To ensure optimal physical properties, membrane glycerophospholipid composition and synthesis are tightly regulated. This review will summarize our current knowledge of factors and processes determining the membrane glycerophospholipid composition of the reference eukaryote S. cerevisiae at the level of molecular species. Extrapolating from relevant model membrane data, we also discuss how modulation of the molecular species composition can regulate membrane physical properties.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947837 | PMC |
| http://dx.doi.org/10.1002/1873-3468.12944 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Continued Treatment with Nintedanib in Patients with Progressive Pulmonary Fibrosis: Data from INBUILD-ON.
Lung
January 2025
National Reference Center for Rare Pulmonary Diseases, Louis Pradel Hospital, Hospices Civils de Lyon, Claude Bernard University Lyon 1, UMR 754, ERN-LUNG, Lyon, France.
Purpose: In the INBUILD trial in patients with progressive pulmonary fibrosis (PPF), nintedanib slowed the decline in forced vital capacity (FVC) versus placebo, with a safety profile characterised mainly by gastrointestinal events. INBUILD-ON, the open-label extension of INBUILD, assessed the safety of nintedanib during longer-term treatment. Data on FVC were collected.
View Article and Find Full Text PDFTargeted Assay Engineering Enhances Bile Salt Hydrolase Activity in Heyndrickxia coagulans ATCC 7050 and Lactiplantibacillus plantarum ATCC 10012.
Curr Microbiol
January 2025
Department of Food Engineering and Technology, Institute of Chemical Technology, Matunga, Mumbai, Maharashtra, India.
The recent emergence of bile salt hydrolase (BSH) enzyme as a therapeutic target reflects its unbound potential in mitigating hypercholesterolemia, obesity, and gastrointestinal issues. However, to bolster its industrial application, optimization of BSH assay lays the cornerstone for enhancing sensitivity, specificity, and reproducibility. The current study delved into optimizing the BSH assay parameters utilizing response surface methodology (RSM) and one-factor-at-a-time (OFAT) method for two novel, natural BSH producers, Heyndrickxia coagulans ATCC 7050 and Lactiplantibacillus plantarum ATCC 10012.
View Article and Find Full Text PDFUncovering the Fungal Community Composition of Alive and Dead Posidonia oceanica Matte.
Microb Ecol
January 2025
Department of Biology, University of Rome Tor Vergata, 00133, Rome, Italy.
Posidonia oceanica retains a large amount of carbon within its belowground recalcitrant structure, the 'matte,' which is characterized by low oxygen availability and biodegradation. Fungi may play a pivotal role in carbon sequestration within the matte, even if little/no information is available. To fill this gap, we profiled fungal communities from the upper and lower layers of alive and dead matte, by using an ITS2-5.
View Article and Find Full Text PDFDevelopment of Fe/SiBr/Si₃N₄/silica fume nanocomposites from recycled metal waste for industrial applications.
Sci Rep
January 2025
Spectroscopy Department, National Research Centre, El Buhouth St., Dokki, Giza, 12622, Egypt.
Due to the high cost of raw materials, this work aims to benefit from metal waste, especially iron (Fe) and silicon bronze, which results from turning workshops and recycling them to obtain nanocomposites for industrial applications. In this respect, Fe/SiBr/SiN/silica fume nanocomposites possessing superior mechanical, wear, and magnetic characteristics have been produced using powder metallurgy (PM) technology. Milled sample particle size, crystal size, and phase composition were investigated using X-ray diffraction (XRD) technique and transmission electron microscopy (TEM).
View Article and Find Full Text PDFTechnological evaluation of stones from the eastern region of the state of São Paulo, Brazil, for railway ballast.
Sci Rep
January 2025
LECIV - Civil Engineering Laboratory, UENF - State University of the North in Rio de Janeiro, Av. Alberto Lamego, 2000, Campos dos Goytacazes, Rio de Janeiro, 28013-602, RJ, Brazil.
The correct choice of a stone aggregate for railway ballast is directly related to the stability, safety, efficiency, and maintenance costs of the track. The aggregate must meet several criteria to ensure it is the most appropriate material. Thus, the present study aimed to evaluate four distinct stones: two granites, a diabase, and a basalt, all mined in the eastern region of the state of São Paulo, Brazil, regarding their applicability as ballast.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!