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Accuracy of lung structure constructed by three-dimensional image analysis with non-enhanced computed tomography.
J Thorac Dis
February 2025
Department of Thoracic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Background: There are few papers on three-dimensional (3D) images of the lungs using non-enhanced computed tomography (CT). This study aimed to investigate the accuracy of 3D images of the lungs using non-enhanced CT.
Methods: The study included 10 consecutive cases for each lung lobe, totalling 50 cases between March and December 2022.
Inter-multisegmental veins (IMSVs): a new positional indication for pulmonary segmentectomy.
J Thorac Dis
February 2025
Department of Thoracic Surgery, Jiangsu Province Hospital and The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Background: Positional indications for sublobar resection have been increasingly focused by clinical surgeons while the surgical strategies for cases involving inter-multisegmental veins (IMSVs) remain underreported. We want to further clarify the positional indications for sublobar resection in patients with clinical T1a-bN0 non-small cell lung cancer (NSCLC).
Methods: The clinical data of 686 patients from August 2021 to July 2022 were retrospectively analyzed.
tailored confining microenvironment for lung cancer spheroids.
Mater Today Bio
April 2025
Shanghai Clinical Research and Trial Center, Shanghai Institute for Advanced Immunochemical Studies (SIAIS), ShanghaiTech University, Shanghai, 201210, China.
The mechanical properties and physical confinement of the extracellular matrix (ECM) are crucial roles in regulating tumor growth and progression. Extensive efforts have been dedicated to replicating the physical characteristics of tumor tissue by developing two-dimensional (2D) and three-dimensional (3D) models. However, it remains a significant challenge to modulate the local microenvironment around the specific cells according to the culture progress.
View Article and Find Full Text PDFThe sagitta in 3D reconstruction of linea alba on routine CT scans is predictive of postoperative burst abdomen.
Hernia
March 2025
Department of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany.
Purpose: Burst abdomen (BA) is a relevant complication after abdominal surgery that causes additional surgical procedures, prolonged hospital stays and long-term morbidity. Several underlying risk factors exist and have been characterized previously. Those risk factors consist of surgical and medical factors.
View Article and Find Full Text PDFUpdate on preclinical models of cancer therapy-related cardiac dysfunction: Challenges and perspectives. A scientific statement of the Heart Failure Association (HFA) of the ESC, the ESC Council of Cardio-Oncology, and the ESC Working Group on Cellular Biology of the Heart.
Eur J Heart Fail
March 2025
Berlin Institute of Health at Charité-Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT), Berlin, Germany.
New anticancer therapies with potential cardiovascular side effects are continuously being introduced into clinical practice, with new and often unexpected toxicities becoming apparent only after clinical introduction. These unknown toxicities should be identified and understood beforehand to better prepare patients and physicians, enabling the implementation of effective treatments. Therefore, there is a crucial need for appropriate preclinical models to understand the biological basis of their cardiotoxicity.
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