AI Article Synopsis
- The study aimed to explore how Alzheimer's disease (AD) affects the understanding of distinctive and nondistinctive semantic features using a simpler task.
- Participants with AD showed significantly lower accuracy in recognizing distinctive features compared to age-matched controls, but their recognition of nondistinctive features remained unaffected.
- The findings suggest that individuals with AD experience specific difficulties with distinct semantic content, even when cognitive demands are minimized.
Article Abstract
Background And Objective: It is widely held that semantic disturbance in Alzheimer disease (AD) involves the loss of distinctive features but the relative sparing of nondistinctive features. Many previous studies of semantic feature disturbance have used cognitively challenging tasks with verbal stimuli that allow for potential cognitive confounds. Our objective was to use a task with lower memory demands to investigate distinctive feature disturbance in AD.
Methods: We used an object decision task to compare the processing of distinctive and nondistinctive semantic features in people with AD and age-matched controls. The task included six conditions based on the relationship between each prime and target object. We tested the processing of distinctive and nondistinctive features by selectively altering distinctive and nondistinctive semantic features between prime and target pairs.
Results: Performance accuracy was significantly lower for participants with AD than for age-matched controls when distinctive features were manipulated, but no difference was found when nondistinctive features were manipulated.
Conclusions: Our results provide evidence of semantic content disturbance in AD in the context of a task with low cognitive demands.
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| http://dx.doi.org/10.1097/WNN.0000000000000140 | DOI Listing |
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