A fluorescent activatable probe for imaging intracellular Mg .

Org Biomol Chem

Medical Research Council Centre for Inflammation Research, The University of Edinburgh, EH16 4TJ Edinburgh, UK.

Published: January 2018

An activatable BODIPY probe for in vitro detection and fluorescence cell imaging of free Mg without interference from Ca is described. Fluorescence amplification of the probe is observed upon detection of physiological concentrations of Mg due to reduced rotation of the fluorophore and effective chelation by a quinolizine-based core.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789582PMC
http://dx.doi.org/10.1039/c7ob02965aDOI Listing

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